Results 151 to 160 of about 474,048 (356)

The Relationship Between Gender and Disability in the Elderly People in Tehran Municipality Pension Organization

open access: yesSālmand, 2017
Objectives Because of increasing geriatric population in Iran, the present study aims to plan, prevent, and mitigate the complications among the retired elderly of the Tehran Municipality Pension Organization and then investigate its relation to gender ...
Helen Noei   +5 more
doaj  

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

open access: yesNature, 2020
Nicole Jane Ankit S. Isaac Ishita Ben A. Philip A. Daniel Almanzar Antony Baghel Bakerman Bansal Barres Beac   +134 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Relationship Between Oral Health and Demographic Characteristics in Retired Elderly People in Iran

open access: yesSālmand, 2019
Objectives The current study aimed to determine the relationship between oral health and demographic characteristics of retired elderly people. Methods & Materials This cross-sectional study was conducted on 158 older adults aged ≥60 years.
Amir Ahmadi   +5 more
doaj  

The central role of DNA damage in the ageing process

open access: yesNature, 2021
B. Schumacher   +3 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Corrigendum: The longitudinal progression of autonomic dysfunction in Parkinson's disease: a 7-year study

open access: yesFrontiers in Neurology, 2023
Charlotte B. Stewart   +9 more
doaj   +1 more source

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