Results 151 to 160 of about 929,250 (364)
MiR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p microRNAs are downregulated in malignant germ cell tumors (GCTs). Combination replenishment of these microRNAs using mimics resulted in growth inhibition in representative cell lines, with consequent downregulation of target genes involved in cell cycle (confirmed by flow cytometry) and ...
Marta Ferraresso+12 more
wiley +1 more source
Introduction and reconciliation of the ROS and aging paradoxes [PDF]
This paper suggests that aging is influenced synthetically by pro-aging factors such as ROS and anti-aging factors such as protective responses. The anti-aging effect may be side effects of retrograde responses motivated against adverse circumstances. ROS may be more closely correlated with metabolism rather than aging.
arxiv
Effects of Sex and Thyroid Hormones on Ageing in Female Rats [PDF]
V. Korenchevsky
openalex +1 more source
'There is No Doubt that I'm Old': Everyday Narratives of Ageing [PDF]
The 3-year Fiction and the Cultural Mediation of Ageing Project (FCMAP), led by a research team in the Brunel Centre for Contemporary Writing (BCCW), and conducted as part of the New Dynamics of Ageing (NDA) programme, began on 1st May 2009 and finished ...
Hubble, N, Tew, P
core
We assessed the associations between the gut microbiota and outcome in metastatic triple‐negative breast cancer patients treated with chemotherapy alone or chemotherapy in combination with immunotherapy. Our data indicate that high gut microbiota alpha diversity was associated with improved clinical outcome and with benefit from immunotherapy.
Andreas Ullern+8 more
wiley +1 more source
Background Recreational parks can play a significant role in older people’s health, with emerging evidence suggesting that changes in the physical environment, such as refurbishments of local parks, can increase park visitations and physical activity ...
Pazit Levinger+5 more
doaj +1 more source
Molecule-dynamic-based Aging Clock and Aging Roadmap Forecast with Sundial [PDF]
Addressing the unavoidable bias inherent in supervised aging clocks, we introduce Sundial, a novel framework that models molecular dynamics through a diffusion field, capturing both the population-level aging process and the individual-level relative aging order.
arxiv
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang+8 more
wiley +1 more source
“On Ageing and Old Age. Basic Problems and Historic Aspects of Gerontology and Geriatrics”. M. D. Grmek. Monographie Biological, vol. v. No. 2. 18 December 1958. [PDF]
Edwin Clarke
openalex +1 more source