Results 211 to 220 of about 474,048 (356)

The Effect of Ageing on the Mechanical and Tribological Properties of Al-Zn-Mg Alloy. [PDF]

Materials (Basel)
Papież J, Leśny K, Zemlik M.
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Enhancement of Apiaceae pre-germination embryo growth, mericarp ageing resilience and germination differs between hormone, gas plasma, and hydropriming technologies. [PDF]

Planta
Fatelnig LMM, Walker M, Grainge G, Hourston JE, Kennedy S, Široká J, Novák O, Tarkowská D, Strnad M, Nakabayashi K, Steinbrecher T, Leubner-Metzger G.   +11 more
europepmc   +1 more source

Research Group Healthy Ageing, Allied Health Care and Nursing

, 2015
Harriëtte Jager-Wittenaar, Cees P. van der Schans, Hans Hobbelen   +2 more
openalex   +1 more source

14DOES THE PRESENCE OF ORTHOSTATIC HYPOTENSION AT BASELINE PREDICT DECLINE IN GLOBAL COGNITION? FINDINGS FROM THE IRISH LONGITUDINAL STUDY ON AGEING (TILDA) [PDF]

, 2018

openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Introducing the WHO ICOPE approach into HIV care: A perspective on healthy ageing in people living with HIV. [PDF]

JAR Life
Guaraldi G, Milic J, Gozzi L, Ambrosio S, Delmonte E, Avanzini I, Castelnuovo B, Mussini C.   +7 more
europepmc   +1 more source

The World report on ageing and health: a policy framework for healthy ageing

The Lancet, 2016
J. Beard, A. Officer, I. A. D. Carvalho, R. Sadana, A. Pot, J. Michel, P. Lloyd-Sherlock, J. Epping-jordan, Geeske Peeters, Wahyu Retno Mahanani, J. Thiyagarajan, S. Chatterji   +11 more
semanticscholar   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Public health responses to ageing in the face of demographic change. [PDF]

Bull World Health Organ
europepmc   +1 more source