Results 51 to 60 of about 938,839 (307)

Ageing makes us dyslexic [PDF]

, 2013
Background: The effects of typical ageing on spoken language are well known: word production is disproportionately affected while syntactic processing is relatively well preserved.
Harley, Trevor A., Jessiman, Lesley J., MacAndrew, Siobhan B. G., Oliver, Tracey M.   +3 more
core   +3 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Improving Electronic Health Record (EHR) data linkages for identifying Aged Care Residents through publicly available data

International Journal of Population Data Science
Introduction Accurate identification of Aged Care residents accessing hospital services is challenging due to multiple hospital Electronic Health Record (EHR) systems and entry points resulting in inconsistent addresses and coding.
Tanya Ravipati, Richard Beare, Velandai Srikanth, Alison Carver, Lei Huang, Rashwinder Dhillon, Nadine E Andrew   +6 more
doaj   +1 more source

IL-6 secretion in osteoarthritis patients is mediated by chondrocyte-synovial fibroblast cross-talk and is enhanced by obesity

Scientific Reports, 2017
Increasing evidence suggests that inflammation plays a central role in driving joint pathology in certain patients with osteoarthritis (OA). Since many patients with OA are obese and increased adiposity is associated with chronic inflammation, we ...
Mark J. Pearson, Dietmar Herndler-Brandstetter, Mohammad A. Tariq, Thomas A. Nicholson, Ashleigh M. Philp, Hannah L. Smith, Edward T. Davis, Simon W. Jones, Janet M. Lord   +8 more
doaj   +1 more source

Sex-specific effects of Cre expression in Syn1Cre mice

Scientific Reports, 2023
The Cre-loxP system has been used to generate cell-type specific mutations in mice, allowing researchers to investigate the underlying biological mechanisms of disease.
Maarouf Baghdadi, Andrea Mesaros, Martin Purrio, Linda Partridge   +3 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Unravelling the transcriptomic symphony of muscle ageing: key pathways and hub genes altered by ageing and caloric restriction in rat muscle revealed by RNA sequencing

BMC Genomics
Age-related muscle wasting, sarcopenia is an extensive loss of muscle mass and strength with age and a major cause of disability and accidents in the elderly.
Gulam Altab, Brian J. Merry, Charles W. Beckett, Priyanka Raina, Inês Lopes, Katarzyna Goljanek-Whysall, João Pedro de Magalhães   +6 more
doaj   +1 more source

Storying Alzheimer's Disease in Lisa Genova's Still Alice [PDF]

, 2014
Taking as its starting point the value of literary studies to work on ageing, this paper explores the contribution of literature to the discourse of ageing and illness, focussing on an illness synonymous with ageing in the cultural imagination ...
Falcus, Sarah
core  

Ageing first passage time density in continuous time random walks and quenched energy landscapes

, 2015
We study the first passage dynamics of an ageing stochastic process in the continuous time random walk (CTRW) framework. In such CTRW processes the test particle performs a random walk, in which successive steps are separated by random waiting times ...
Godec, Aljaz, Krusemann, Henning, Metzler, Ralf   +2 more
core   +1 more source

Reminiscence and ageing [PDF]

, 1998
This paper questions assumptions about reminiscence and looks at definitions of it. Functions of different types of reminiscence are examined and distinctions are drawn between these and autobiographical memories. Methodologies of eliciting reminiscences
Cohen, Gillian, Taylor, Stephanie
core   +1 more source