Results 61 to 70 of about 474,048 (356)

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura, Kentaro Ueno, Takuro Nishikawa, Yoshihiro Takahashi, Koji Nakae, Yasuhiro Okamoto   +5 more
wiley   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

The association between a fracture risk tool and frailty: Geelong Osteoporosis Study

BMC Geriatrics, 2020
Background Frailty is characterised by age-related declines in physical, psychological and social functioning. Features of frailty overlap with risk factors for fragility fractures.
Monica C. Tembo, Kara L. Holloway-Kew, Mohammadreza Mohebbi, Sophia X. Sui, Sarah M. Hosking, Sharon L. Brennan-Olsen, Lana J. Williams, Mark A. Kotowicz, Julie A. Pasco   +8 more
doaj   +1 more source

The interaction between ageing and Alzheimer's disease: insights from the hallmarks of ageing

Translational Neurodegeneration
Ageing is a crucial risk factor for Alzheimer’s disease (AD) and is characterised by systemic changes in both intracellular and extracellular microenvironments that affect the entire body instead of a single organ.
Yuqing Liu, Yejun Tan, Zheyu Zhang, Min Yi, Lemei Zhu, Weijun Peng   +5 more
semanticscholar   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

The challenges of muscle biopsy in a community based geriatric population

BMC Research Notes, 2018
Objectives To describe the difficulties of obtaining muscle samples using a Bergstrom needle technique in a frail older adult population. The data were obtained from a study primarily investigating immunosenescence in frailty.
Daisy Wilson, Leigh Breen, Janet M. Lord, Elizabeth Sapey   +3 more
doaj   +1 more source

Rocket Science: The Effect of Spaceflight on Germination Physiology, Ageing, and Transcriptome of Eruca sativa Seeds [PDF]

, 2020
Jake O. Chandler, Fabian B. Haas, Safina Khan, Laura Bowden, Michael Ignatz, Eugenia M. A. Enfissi, Frances Gawthrop, Alistair Griffiths, Paul D. Fraser, Stefan A. Rensing, Gerhard Leubner‐Metzger   +10 more
openalex   +1 more source

Ageing in Africa as the Youngest Region: Research-Policy Emergence [PDF]

, 2022
Jaco Hoffman
openalex   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Client characteristics and outcomes of the Australian short-term restorative care programme: a cohort study

BMC Health Services Research
Background Restorative care is a goal-oriented, time-limited, multidisciplinary approach to address functional decline in older adults. Within Australia, one form of restorative care available to community-dwelling older adults is the Short-Term ...
Lindsey Brett, Angela Collins, Kylie Lemsing, Christopher J. Poulos   +3 more
doaj   +1 more source