Results 31 to 40 of about 38,974 (312)

It’s Big Mouth!

open access: yesBody, Space & Technology Journal, 2021
The intermedial performance displayed in this video essay, highlights the need to re envisage Laura Mulvey’s 1975 theory of the male gaze in relation to the female-identifying ageing woman.
Sophie Swoffer
doaj   +2 more sources

Metchnikoff’s scientific ideas and modernity

open access: yesAnnals of Mechnikov's Institute, 2020
On May 15, 2015, we celebrated the 170th anniversary of the Ilya Metchnikoff, the author of the hypothesis about parenchymella, the father of cellular immunology and inflammation theory, founder of gerontology, aging and longevity science.
N Popov, T Kolotova
doaj  

Aging theory and aging control

open access: yesNippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 2010
1980年以降の分子生物学の発展により,加齢生物学の進展が目覚しい.特に,線虫や酵母菌を用いた長寿遺伝子の発見により,加齢生物学と老化の病理学を再考する必要に迫られている.インスリンシグナルやミトコンドリアの代謝は動物の寿命を制御しているばかりでなく,老化をも制御している可能性が示唆されている.一方,遺伝性早老症の研究から,ゲノムの安定性と修復機構が老化のプロセスに関与していることが分かってきた.高齢期に発症してくる病気はヒトの寿命を規定していることから,老化のプロセスは寿命を規定しうる重要な要因である.1950年以来提唱され続けている老化学説であるフリーラジカル学説と最近の長寿遺伝子の関係やゲノム修復機構との関連性,テロメアと細胞老化の関係など最新の老化研究の考え方を解説する.
openaire   +3 more sources

Theories of biological aging

open access: yesExperimental Gerontology, 1985
Experimental Gerontology 20 (1985) 145-159. doi:10.1016/0531-5565(85)90032-4 ; Received by publisher: 0000-01-01 ; Harvest Date: 2016-01-04 12:22:36 ; DOI:10.1016/0531-5565(85)90032-4 ; Page Range: 145 ...
Center for Gerontological Studies, University of Florida 3357 GPA, Gaineville, Florida 32611 USA ( host institution )   +1 more
openaire   +3 more sources

Graying the Cyborg Revisited. How Age Matters when Technologies Move under the Skin

open access: yesTecnoscienza, 2021
Feminist scholars were among the first to argue for the importance of including ageing and later life in STS research. Remarkably, most studies on technoscience and ageing only address technologies external to bodies.
Nelly Oudshoorn
doaj   +1 more source

A Microcirculatory Theory of Aging [PDF]

open access: yesAging and disease, 2019
Aging is the progressive decline of physiological functions necessary for survival and reproduction. In gaining a better understanding of the inevitable aging process, the hope is to preserve, promote, or delay healthy aging through the treatment of common age-associated diseases.
openaire   +2 more sources

Perceptions of active ageing in Britain: divergences between minority ethnic and whole population samples

open access: yes, 2009
Objective: to identify perceptions of, and associations with, active ageing among ethnically diverse and homogeneous samples of older people in Britain.
Bowling, Ann, Bowling, A
core   +1 more source

Ageing and Mobility- Making the Connections [PDF]

open access: yes, 2010
Spatial mobility in later life has received much attention by researchers and policy makers in recent years as part of discourses around active ageing and ageing independently.
Ziegler, Rahel Friederike   +1 more
core  

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

When a theory of aging ages badly [PDF]

open access: yesCellular and Molecular Life Sciences, 2009
According to the widely acknowledged mitochondrial free radical theory of aging (MFRTA), the macromolecular damage that results from the production of toxic reactive oxygen species (ROS) during cellular respiration is the cause of aging. However, although it is clear that oxidative damage increases during aging, the fundamental question regarding ...
Jérôme, Lapointe, Siegfried, Hekimi
openaire   +2 more sources

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