Results 41 to 50 of about 38,974 (312)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
The changing understanding of ageing. Part 3: Diseases of ageing [PDF]
Veterinaria Italiana, 2011 This third and final paper in this series considers ageing mechanisms across species, with emphasis on conserved metabolic pathways that relate to disease. The growth hormone (GH)-insulin-like growth factor (IGF-1)-insulin axis continues as an example of
Dennis F. Lawler
doaj
Cogent Medicine, 2017 There is a stark contrast between the activity and disengagement theories in terms of what they say is the level of social engagement and physical activity associated with the population of elderly people.
Nestor Asiamah
doaj +1 more source
International Journal of Ageing and Later Life, 2012 From an international perspective, media representations of population ageing have been described as apocalyptic in character. In this article, we analyse the way population ageing is represented in three Swedish newspapers: Aftonbladet, Dagens Nyheter ...
Anna Sofia Lundgren, Karin Ljuslinder
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker +11 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
The impact of peroxisomes on cellular ageing and death
Frontiers in Oncology, 2012 Peroxisomes are ubiquitous eukaryotic organelles, which perform a plethora of functions including hydrogen peroxide metabolism and β-oxidation of fatty acids.
Selvambigai eManivannan +3 more
doaj +1 more source
The Mitochondrial Theory of Aging
Neurosignals, 2001 Mitochondria are not only the main source of energy for most eukaryotic cells, but also the main source of free radicals. These reactive molecules can damage all components of a cell such as membranes, proteins and DNA. Therefore they have long been suspected to be involved in the biological aging process.
openaire +2 more sources
Editorial Ageing with digital technologies:from theory to agency and practice
, 2022 The title of this special issue, ‘Ageing with digital technologies’ points to two of the growing challenges facing the twenty first century. Namely, the changing demographic structure of societies connected to ageing populations on the one hand, and ...
Kania-Lundholm, Magdalena +4 more
core +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source