Results 91 to 100 of about 6,568,437 (291)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Agency submission to the Nutrition Advisory Group
, 1993 The Agency was established by the Government in September 1986 under the Combat Poverty Agency Act Under this Act the Agency has a statutory duty to advise and make recommendations to the Government on all aspects of economic and social planning in ...
Combat Poverty Agency (CPA)
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Public Health Agency Self- Harm Symposium Conference Report
, 2015 Public Health Agency Self- Harm Symposium 27 February 2015, Conference ...
Public Health Agency
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The Agency Advantage of Debt over the Lifecycle of the Firm
The Journal of Entrepreneurial Finance, 1996 The question of an `optimal' capital structure of a firm has been studied for publicly listed businesses for years. From these studies, agency theory has emerged as a good way to understand a firm's capital structure.
Ed Vos, Carolyn Forlong
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Texas Education Agency Annual Report
, 2019 The report describe the Texas Education Agency strategic plan, recruit, support and retain teachers and principals, build a foundation of reading and math, connect high school to career and college, improve low-performing schools, enrollment and ...
Texas Education Agency
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Education SciencesOnline and hybrid learning are now an established part of higher education, yet questions remain about what constitutes quality in these learning environments.
Maggie Katherine Hartnett, Jean Jacoby
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Homeless Agency: making it home: annual report: 2004.
, 2005 The Homeless Agency is a partnership body that was established as part of the Government strategy on homelessness in May 200 l. It is responsible for the planning and co-ordination of the delivery of quality services to people who are homeless in ...
Homeless Agency
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