Results 71 to 80 of about 209,221 (295)

Professional Identity in a Multi-agency Team [PDF]

open access: yes, 2012
Although multi-agency working isn’t a new concept, the previous Labour government encouraged professionals and services to work collaboratively and in partnership to address issues of social exclusion, poverty and deprivation in order to provide support ...
PRATT, JEANNE,MARIE
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Agency theory : an extended conceptualisation and reformation

open access: yes, 2005
The theory of Agency, specifically that developed by Jesen and Meckling (1976), will be the subject of examination. Agency theory has been the subject of extensive research since its introduction in modern form by Jensen and Meckling (1976).
Temel-Candemir, Nurcan
core  

Agency theory, corporate governance and corruption: an integrative literature review approach

open access: yesCogent Social Sciences
The aim of this study is to revisit the concept of the separation between ownership and control through reviewing studies on agency theory, governance, and corruption.
Mamdouh Abdulaziz Saleh Al-Faryan
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Agency theory and its challenges in public administration [PDF]

open access: yesمطالعات مدیریت بهبود و تحول, 2002
در این مقاله، ضمن تشریح تئوری کارگزاری و مفروضات اساسی آن، برخی از انواع قراردادهای رایج کارگزاری با عناوینی همچون قرارداد جبران خدمت مبتنی بر رفتار، قرارداد مبتنی بر نتایج و قرارداد مبتنی بر حقوق، قرارداد مبتنی بر هزینه خدمات و قرارداد مبتنی بر هزینه ...
seyed mehdi alvani, mirali seyed naghavi
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Pengaruh Biaya Agensi, Tahap Daur Hidup Perusahaan, dan Regulasi terhadap Kebijakan Dividen pada Perusahaan Manufaktur di Bursa Efek Indonesia

open access: yesJurnal Manajemen dan Wirausaha, 2009
The purpose of the article was to investigation the influence agency cost that proxy with Dispersion of Ownership; Institutional Ownership; Free Cash Flow, life cycle of the firm and industries regulation on dividend policy in manufacture industry ...
Djumahir Djumahir
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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