Results 51 to 60 of about 1,981,680 (297)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
A Critical Perspective towards Agency Theory
Jurnal Akuntansi Multiparadigma, 2013 The aim of this research is explaining the nature, function, role and critics towards agency theory. Qualitative method was employed in this research.
Kartika Putri Kumalasari, Made Sudarma
doaj
Theorizing Audience and Spectatorial Agency [PDF]
, 2014 This chapter analyses Georgian audiences and spectatorial agency through several lenses: psychoanalytic film theory, theories of the public sphere and of mass publicity, and media studies of cultural convergence.
Bolton, Betsy
core +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Classical and modern concepts of corporate governance (Stewardship Theory and Agency Theory)
Management, 2015 The main issues in efficiency of a company as an organisation are relations between the Supervisory Board and the Management Board of a company, and the methods of functioning of Supervisory Boards in governance systems of a company.
Glinkowska Beata, Kaczmarek Bogusław
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Theory-Praxis: Principals vs. Agents among Namibian Public Enterprises
iRASD Journal of ManagementIn Namibia, public enterprise (PE) agents are obligated to prioritize and advance the interests of their principals (namely the government). However, recent trends have seen the proliferation of conflicts arising due to impediments such as information ...
Ralph Marenga
doaj +1 more source
, 2007 Abstract In decision theory, it is almost universally presupposed that agency is invested in individuals: each person acts on her own preferences and beliefs. A person’s preferences may take account of the effects of her actions on other people; she may, for example, be altruistic or have an aversion to inequality.
Sugden, R, Gold, N
openaire +3 more sources