Results 51 to 60 of about 688,654 (273)

Designing a Simulation Model for Organizational Agility Development in Hospitals of Ardabil Province, Iran [PDF]

بیمارستان, 2023
Background and objective: As a critical factor for hospital effectiveness, agility uncovers the way such organizations react to internal and external changes.
Hossein Rahimi Klour, Seyed Ali Naghavi
doaj  

Evoplex: A platform for agent-based modeling on networks

, 2019
Agent-based modeling and network science have been used extensively to advance our understanding of emergent collective behavior in systems that are composed of a large number of simple interacting individuals or agents.
Cardinot, Marcos, Griffith, Josephine, O'Riordan, Colm, Perc, Matjaž   +3 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Agent-Based Modeling of Intracellular Transport

, 2011
We develop an agent-based model of the motion and pattern formation of vesicles. These intracellular particles can be found in four different modes of (undirected and directed) motion and can fuse with other vesicles. While the size of vesicles follows a
A. Dautry-Varsat, A.-T. Dinh, A.-T. Dinh, F. Schweitzer, F. Schweitzer, G. Doherty, G. Hannon, J. Mercer, M. Birbaumer, M. Marsh, M. Roth, P.D. Fiore, R. Mach, S. Conner, W. Ebeling, W. Ebeling   +15 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Private Agent-Based Modeling

The practical utility of agent-based models in decision-making relies on their capacity to accurately replicate populations while seamlessly integrating real-world data streams. Yet, the incorporation of such data poses significant challenges due to privacy concerns.
Chopra, A, Quera-Bofarull, A, Giray-Kuru, N, Wooldridge, M, Raskar, R   +4 more
openaire   +3 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

An agent-based model facilitating stakeholder engagement in management of estuaries along the Texas Gulf Coast (USA)

MethodsX
We describe an agent-based model purposed for social learning, which was developed by stakeholders, with the technical assistance of professional modelers, to facilitate stakeholder involvement in modeling issues related to the development of an adaptive
Hsiao-Hsuan Wang, Paulami Banerjee, Chara J. Ragland, William E. Grant, Tarla R. Peterson   +4 more
doaj   +1 more source

Improving Agent Based Modeling of Critical Incidents [PDF]

Journal of Systemics, Cybernetics and Informatics, 2010
Agent Based Modeling (ABM) is a powerful method that has been used to simulate potential critical incidents in the infrastructure and built environments.
Robert Till
doaj