Results 61 to 70 of about 148,957 (266)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
MethodsXWe describe an agent-based model purposed for social learning, which was developed by stakeholders, with the technical assistance of professional modelers, to facilitate stakeholder involvement in modeling issues related to the development of an adaptive
Hsiao-Hsuan Wang +4 more
doaj +1 more source
Improving Agent Based Modeling of Critical Incidents [PDF]
Journal of Systemics, Cybernetics and Informatics, 2010 Agent Based Modeling (ABM) is a powerful method that has been used to simulate potential critical incidents in the infrastructure and built environments.
Robert Till
doaj
AGENT BASED MODELING: FINE-SCALE SPATIO-TEMPORAL ANALYSIS OF PERTUSSIS [PDF]
ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2017 In epidemiology, spatial and temporal variables are used to compute vaccination efficacy and effectiveness. The chosen resolution and scale of a spatial or spatio-temporal analysis will affect the results.
D. A. Mills
doaj +1 more source
Agent-based modeling: A revolution? [PDF]
Proceedings of the National Academy of Sciences, 2002 A clear consensus among the papers in this Colloquium is that agent-based modeling is a revolutionary development for social science. However, the reasons to expect this revolution lie more in the potential seen in this tool than through realized results. In order for the anticipated revolution to occur, a series of challenges must be met.
openaire +2 more sources
An Agent-Based Approach to Immune Modelling [PDF]
, 2006 This study focuses on trying to understand why the range of experience with respect to HIV infection is so diverse, especially as regards to the latency period. The challenge is to determine what assumptions can be made about the nature of the experience of antigenic invasion and diversity that can be modelled, tested and argued plausibly.
Perrin, Dimitri +3 more
openaire +3 more sources
Platforms and methods for agent-based modeling [PDF]
Proceedings of the National Academy of Sciences, 2002 The range of tools designed to help build agent-based models is briefly reviewed. It is suggested that although progress has been made, there is much further design and development work to be done. Modelers have an important part to play, because the creation of tools and models using those tools proceed in a dialectical relationship.
Gilbert, Nigel, Bankes, Steven
openaire +4 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
An Overview of Agent-Based Models for Transport Simulation and Analysis
Journal of Advanced Transportation, 2022 This article presents an overview of the agent-based modeling and simulation approach and its recent developments in transport fields, with the purpose of discovering the advantages and gaps and encouraging more valuable investigations and applications ...
Jiangyan Huang +5 more
doaj +1 more source