Results 81 to 90 of about 148,957 (266)
The Unrecognized Death Toll of COVID-19 in the United States
The Lancet Regional Health. Americas, 2021 Seyed M. Moghadas, Alison P. Galvani
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Pedestrian Attribute Analysis Using Agent-Based Modeling
Applied Sciences, 2020 Crossing a road outside of a crosswalk is a major cause of pedestrian fatalities. The aim of this study was to investigate this type of behavior for different pedestrian attributes in terms of risk and gap acceptance using agent-based modeling techniques.
Khaled Shaaban, Karim Abdelwarith
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
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Workshop on Agent-Based Modeling [PDF]
, 2007 After the success of the first workshop of Agent-based approach in Economic and Social Complex Systems (AESCS) in Shimane, 2001, we have held a similar workshop in Niigata, 2003. The title is International Workshop on Agent-Based Modeling. The aims and scope are summarized as follows: Agent-Based Modeling has become one of major techniques to design ...
openaire +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
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Data & PolicyEffective enforcement of laws and regulations hinges heavily on robust inspection policies. While data-driven approaches to testing the effectiveness of these policies are gaining popularity, they suffer significant drawbacks, particularly a lack of ...
Eunice Koid +2 more
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Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
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A Decentralized Solution for Transmission Expansion Planning: Getting Inspiration from Nature
Energies, 2019 Transmission expansion planning is a problem of considerable complexity where classical optimization techniques are unable to handle large case studies. Decomposition and divide-and-conquer strategies have been applied to this problem.
Sara Lumbreras +4 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
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Business Process Modeling and Efficiency Improvement through an Agent-Based Approach [PDF]
Journal of Systemics, Cybernetics and Informatics, 2013 A comprehensive knowledge of a company's organizational mechanisms is a fundamental prerequisite for good management practices and effective governance, especially in the banking industry where efficiency and effectiveness have recently been becoming ...
Dario Russo +3 more
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