Results 51 to 60 of about 694,255 (290)
Designing a Simulation Model for Organizational Agility Development in Hospitals of Ardabil Province, Iran [PDF]
بیمارستان, 2023 Background and objective: As a critical factor for hospital effectiveness, agility uncovers the way such organizations react to internal and external changes.
Hossein Rahimi Klour, Seyed Ali Naghavi
doaj
Evoplex: A platform for agent-based modeling on networks
, 2019 Agent-based modeling and network science have been used extensively to advance our understanding of emergent collective behavior in systems that are composed of a large number of simple interacting individuals or agents.
Cardinot, Marcos +3 more
core +1 more source
Empirical analysis and agent-based modeling of Lithuanian parliamentary elections [PDF]
, 2017 In this contribution we analyze a parties' vote share distribution across the polling stations during the Lithuanian parliamentary elections of 1992, 2008 and 2012. We find that the distribution is rather well fitted by the Beta distribution.
Kononovicius, A.
core +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The practical utility of agent-based models in decision-making relies on their capacity to accurately replicate populations while seamlessly integrating real-world data streams. Yet, the incorporation of such data poses significant challenges due to privacy concerns.
Chopra, A +4 more
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
MethodsXWe describe an agent-based model purposed for social learning, which was developed by stakeholders, with the technical assistance of professional modelers, to facilitate stakeholder involvement in modeling issues related to the development of an adaptive
Hsiao-Hsuan Wang +4 more
doaj +1 more source
Improving Agent Based Modeling of Critical Incidents [PDF]
Journal of Systemics, Cybernetics and Informatics, 2010 Agent Based Modeling (ABM) is a powerful method that has been used to simulate potential critical incidents in the infrastructure and built environments.
Robert Till
doaj