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Canadian Journal of Infectious Diseases and Medical Microbiology, 2015 BACKGROUND: Despite significant research efforts in Canada, real application of modelling in public health decision making and practice has not yet met its full potential. There is still room to better address the diversity of the Canadian population and
Seyed M Moghadas +3 more
doaj +1 more source
Comparison of Different Simulations Methods in Case of Service-Providing Companies [PDF]
Interdisciplinary Description of Complex Systems, 2015 Optimal functioning of a market oriented company, in particular the service providing company, is an important example of optimisation of actions within the context of complex environment.
Biserka Runje +2 more
doaj +1 more source
Rule-based Modelling and Tunable Resolution [PDF]
, 2009 We investigate the use of an extension of rule-based modelling for cellular signalling to create a structured space of model variants. This enables the incremental development of rule sets that start from simple mechanisms and which, by a gradual ...
Russ Harmer +2 more
core +5 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The Repast Simulation/Modelling System for Geospatial Simulation [PDF]
, 2007 The use of simulation/modelling systems can simplify the implementation of agent-based models. Repast is one of the few simulation/modelling software systems that supports the integration of geospatial data especially that of vector-based geometries ...
Crooks, AT
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Multi-Agent-Based Macroeconomic Modelling
Theory, Methodology, Practice, 2019 Macroeconomic modelling emerged at the end of the 20th century and by the first decade of the 21st century it had been widely accepted. However, the financial crisis of 2007 followed by the real economy crisis exposed the weaknesses of dynamic ...
Sándor Karajz
doaj +2 more sources
Fractional modeling of COVID-19 dynamics
CQD Revista Eletrônica Paulista de Matemática, 2022 The present work seeks to provide a comparison between the classical epidemiological model using ordinary differential equations and an approach through the fractional calculus, using the COVID-19 pandemic in Brazil as a case study.
Micaeli Mendola Theodoro +3 more
doaj
Going Stupid with EcoLab [PDF]
, 2006 In 2005, Railsback et al. proposed a very simple model ({\em Stupid Model}) that could be implemented within a couple of hours, and later extended to demonstrate the use of common ABM platform functionality.
Standish, Russell K.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source