Results 71 to 80 of about 459,186 (346)
The practical utility of agent-based models in decision-making relies on their capacity to accurately replicate populations while seamlessly integrating real-world data streams. Yet, the incorporation of such data poses significant challenges due to privacy concerns.
Chopra, A +4 more
openaire +3 more sources
Multi-Objective Calibration For Agent-Based Models [PDF]
, 2004 Agent-based modelling is already proving to be an immensely useful tool for scientific and industrial modelling applications. Whilst the building of such models will always be something between an art and a science, once a detailed model has been built ...
Rogers, Alex, von Tessin, Peter
core
Drivers’ behaviour modelling for virtual worlds [PDF]
, 2013 In this paper we present a study that looks at modelling drivers’ behaviour with a view to contribute to the problem of road rage. The approach we adopt is based on agent technology, particularly multi-agent systems.
Bechkoum, Kamal +2 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Investigating biocomplexity through the agent-based paradigm. [PDF]
, 2015 Capturing the dynamism that pervades biological systems requires a computational approach that can accommodate both the continuous features of the system environment as well as the flexible and heterogeneous nature of component interactions.
Kaul, H, Ventikos, Y
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Chemical industry supply chain optimisation using agent-based modelling [PDF]
, 2013 In this paper we present an application of Supply Chain Spread Sheet Simulator (SCSS) in a task dealing with chemical industry supply chain redesign and optimisation.
Dyntar, Jakub, Škvor, Jan
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Complex Effects of Telecouplings on Forest Dynamics: An Agent-Based Modeling Approach [PDF]
, 2021 Hongbo Yang +5 more
openalex +1 more source