Results 61 to 70 of about 25,149,472 (302)

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Multi-Agent-Based Macroeconomic Modelling

Theory, Methodology, Practice, 2019
Macroeconomic modelling emerged at the end of the 20th century and by the first decade of the 21st century it had been widely accepted. However, the financial crisis of 2007 followed by the real economy crisis exposed the weaknesses of dynamic ...
Sándor Karajz
doaj   +2 more sources

Fractional modeling of COVID-19 dynamics

CQD Revista Eletrônica Paulista de Matemática, 2022
The present work seeks to provide a comparison between the classical epidemiological model using ordinary differential equations and an approach through the fractional calculus, using the COVID-19 pandemic in Brazil as a case study.
Micaeli Mendola Theodoro, Thomas Nogueira Vilches, Rubens de Figueiredo Camargo, Paulo Fernando de Arruda Mancera   +3 more
doaj  

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis

BMC Infectious Diseases
Background Understanding the key drivers of SARS-CoV-2 transmission is essential for shaping effective public health strategies. However, transmission risk is subject to substantial heterogeneity related to disease severity, age, sex, comorbidities, and ...
Dewan Md. Sumsuzzman, Yang Ye, Zhen Wang, Abhishek Pandey, Joanne M. Langley, Alison P. Galvani, Seyed M. Moghadas   +6 more
doaj   +1 more source

EURACE: A massively parallel agent-based model of the European economy [PDF]

, 2008
Deissenberg C, van der Hoog S, Dawid H. EURACE: A massively parallel agent-based model of the European economy. Applied Mathematics and Computation. 2008;204(2):541-552.EURACE is a major European attempt to construct an agent-based model of the European ...
Dawid, Herbert, van der Hoog, Sander ; https://orcid.org/, Dawid, Herbert ; https://orcid.org/, Deissenberg, Christophe, van Der Hoog, Sander   +4 more
core   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

A practical generation-interval-based approach to inferring the strength of epidemics from their speed

Epidemics, 2019
Infectious disease outbreaks are often characterized by the reproduction number R and exponential rate of growth r. R provides information about outbreak control and predicted final size, but estimating R is difficult, while r can often be estimated ...
Sang Woo Park, David Champredon, Joshua S. Weitz, Jonathan Dushoff   +3 more
doaj   +1 more source

ABMU: An Agent-Based Modelling Framework for Unity3D

SoftwareX, 2021
The field of Agent-Based Modelling (ABM) has expanded significantly since its emergence, with a plethora of ABM development frameworks available to researchers today.
Kostas Cheliotis
doaj   +1 more source

Agent-Based Models of the Labor Market [PDF]

, 2018
The chapter reviews the literature concerning agent-based labor market models by tracing its roots to the microsimulation literature and surveying a selection of con- tributions made since the work by Bergmann and Eliasson et al. Agent-based models have been applied to explain stylized facts of labor markets as well as labor market policy evaluations ...
Michael Neugart, RICHIARDI, MATTEO GUIDO
openaire   +3 more sources