Results 61 to 70 of about 459,186 (346)

Impact of disease severity, age, sex, comorbidity, and vaccination on secondary attack rates of SARS-CoV-2: a global systematic review and meta-analysis

BMC Infectious Diseases
Background Understanding the key drivers of SARS-CoV-2 transmission is essential for shaping effective public health strategies. However, transmission risk is subject to substantial heterogeneity related to disease severity, age, sex, comorbidities, and ...
Dewan Md. Sumsuzzman, Yang Ye, Zhen Wang, Abhishek Pandey, Joanne M. Langley, Alison P. Galvani, Seyed M. Moghadas   +6 more
doaj   +1 more source

ABMU: An Agent-Based Modelling Framework for Unity3D

SoftwareX, 2021
The field of Agent-Based Modelling (ABM) has expanded significantly since its emergence, with a plethora of ABM development frameworks available to researchers today.
Kostas Cheliotis
doaj   +1 more source

Agent-based pedestrian modelling [PDF]

, 2003
When the focus of interest in geographical systems is at the very fine scale, at the level of streets and buildings for example, movement becomes central to simulations of how spatial activities are used and develop.
Batty, Michael
core  

Modelling Social Care Provision in An Agent-Based Framework with Kinship Networks [PDF]

, 2019
Current demographic trends in the UK include a fast-growing elderly population and dropping birth rates, and demand for social care amongst the aged is rising. The UK depends on informal social care -- family members or friends providing care -- for some
Gostoli, Umberto, Silverman, Eric
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Impact of information dissemination and behavioural responses on epidemic dynamics: A multi-layer network analysis

Infectious Disease Modelling
Network models adeptly capture heterogeneities in individual interactions, making them well-suited for describing a wide range of real-world and virtual connections, including information diffusion, behavioural tendencies, and disease dynamic ...
Congjie Shi, Silvio C. Ferreira, Hugo P. Maia, Seyed M. Moghadas   +3 more
doaj   +1 more source

A practical generation-interval-based approach to inferring the strength of epidemics from their speed

Epidemics, 2019
Infectious disease outbreaks are often characterized by the reproduction number R and exponential rate of growth r. R provides information about outbreak control and predicted final size, but estimating R is difficult, while r can often be estimated ...
Sang Woo Park, David Champredon, Joshua S. Weitz, Jonathan Dushoff   +3 more
doaj   +1 more source

Implementation of Agent Based Modelling to Observe the Evacuating Behavior at Faculty of Engineering Building, University of Bengkulu, Indonesia

Journal of the Civil Engineering Forum, 2022
Evacuation is an important issue during the occurrence of an earthquake, due to the influence of people’s responsive behaviours to the disaster. This indicates the occurrence of overcrowded conditions, which causes the conflict of people’s movement.
Hardiansyah, Wida Fitrianip, Annisa Fitria Edriani, Robi Hardiansyah, Rizka Lestyanti, Lindung Zalbuin Mase   +5 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source