Results 71 to 80 of about 5,285,567 (223)

Total Syntheses and Anti-Inflammatory Studies of Three Natural Coumarins: Glycycoumarin, Glycyrin, and 3-O-Methylglycyrol

Molecules
Licorice (Glycyrrhiza uralensis Fisch), a significant traditional Chinese herbal medicine, has been extensively utilized in China to treat various ailments.
Ting Peng, Bin Long, Xiuli Yang, Na Wang, Ximeng Wang, Yujiao He, Hongbo Dong   +6 more
doaj   +1 more source

Deterministic meeting of sniffing agents in the plane

, 2017
Two mobile agents, starting at arbitrary, possibly different times from arbitrary locations in the plane, have to meet. Agents are modeled as discs of diameter 1, and meeting occurs when these discs touch.
A Dessmark, A Pelc, D Baba, E Anderson, E Kranakis, J Chalopin, J Czyzowicz, J Czyzowicz, M Cieliebak, P Flocchini, P Flocchini, S Alpern, S Das, Y Dieudonné, Y Dieudonné   +14 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Creating agent platforms to host agent-mediated services that share resources [PDF]

, 2002
After a period where the Internet was exclusively filled with content, the present efforts are moving towards services, which handle the raw information to create value from it.
Mérida-Campos, C, Pujol, J M, Vázquez Salceda, Javier   +2 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Immunoprevention of non-viral cancers: challenges and strategies for early intervention

Cancer Cell International
While the effects of cancer vaccines have been extensively studied in the therapeutic setting, research has been more limited in the areas of cancer prevention and interception.
Kajal Biswas, Lillian S. Kuo, Robert H. Shoemaker, Altaf Mohammed   +3 more
doaj   +1 more source

OPACA: Toward an Open, Language- and Platform-Independent API for Containerized Agents

IEEE Access
While multi-agent frameworks can provide many advanced features, they often suffer from not being able to seamlessly interact with the outside world, e.g., with web-services or other multi-agent frameworks.
Benjamin Acar, Tobias Kuster, Oskar F. Kupke, Robert K. Strehlow, Marc Guerreiro Augusto, Fikret Sivrikaya, Sahin Albayrak   +6 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Animated virtual agents to cue user attention: comparison of static and dynamic deictic cues on gaze and touch responses [PDF]

, 2011
This paper describes an experiment developed to study the performance of virtual agent animated cues within digital interfaces. Increasingly, agents are used in virtual environments as part of the branding process and to guide user interaction.
Martinez, Santiago, Scott-Brown, Kenneth C., Sloan, Robin J. S., Szymkowiak, Andrea   +3 more
core