Results 181 to 190 of about 4,877,507 (345)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Pesquisa de agentes entomopatogénicos na Ilha Terceira (Açores). [PDF]

open access: yes, 1996
IX Expedição Científica do Departamento de Biologia - Terceira 1994.Durante a "Expedição Científica Terceira 1994" fez-se a recolha de amostras de solo para pesquisa de nemátodos e fungos entomopatogénicos no âmbito do projecto de colecção e ...
Aguiar, Paula   +5 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

RESTRICCIONES EN EL DISEÑO Y APLICACIÓN DE LA REFORMA TRIBUTARIA DE 1845: UN NUEVO ENFOQUE [PDF]

open access: yes
En este trabajo se analiza la reforma tributaria de 1845 en el momento interno y en el período externo, teniendo en cuenta los factores y los agentes que influyeron en la misma.
Rafael Vallejo Pousada
core  

Segurança Alimentar: Controlo de Agentes Patogénicos no Presunto [PDF]

open access: yes, 2013
Cerca de 75% das doenças que nos últimos anos tem afectado a espécie humana tem origem nos animais e seus produtos, tendo muitas delas origem alimentar.
Potes, M.E.
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

APOYO A LA TOMA DE DECISIONES EN UN OBSERVATORIO TECNOLÓGICO INCORPORANDO PROACTIVIDAD / DECISION-MAKING SUPPORT IN A TECHNOLOGY OBSERVATORY BY INCORPORATING PROACTIVITY

open access: yesRevista Científica de Ingeniería Industrial, 2013
Buscar y procesar información tiene un gran impacto en varias profesiones, es por ello que recuperarla y compartir los resultados se convierte en un tema esencial.
Mailyn Moreno-Espino   +3 more
doaj  

Metodología para el Desarrollo Automatizado de Aplicaciones Seguras Basadas en Agentes Móviles [PDF]

open access: yes, 2006
En este trabajo presentamos una metodología para el diseño de aplicaciones basadas en agentes móviles seguros, y unas herramientas para aplicar esta metodología.
Garrigues Olivella, Carles   +2 more
core  

CAB-O-SIL .......instant agent ... agent... agent [PDF]

open access: yesChemical & Engineering News Archive, 1960
openaire   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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