Results 71 to 80 of about 4,273 (188)

Improved prediction of symptomatic type 1 diabetes using a luciferase‐based assay to measure (pro)insulin autoantibodies

Diabetic Medicine, EarlyView.
Abstract Introduction Insulin autoantibodies (IAA) are key predictors of type 1 diabetes, particularly in young children. Micro‐radiobinding assays (RBA) are the gold standard for IAA measurement but have limitations. We assessed whether a luciferase immunoprecipitation system (LIPS) assay improved diabetes risk assessment.
Rebecca C. Wyatt, Cristina Brigatti, Sian L. Grace, Claire L. Williams, Ilaria Marzinotto, Ben T. Gillard, Elena Bazzigaluppi, Deborah Shoemark, Michela A.‐M. Chandler, Peter Achenbach, Lorenzo Piemonti, BOX Study Group, Isabel Wilson, Rachel Aitken, Ilana Kelland, Clare Megson, Chitrabhanu Ballav, Atanu Dutta, Michelle Russell‐Taylor, Rachel Besser, James Bursell, Shanthi Chandran, Sejal Patel, Anne Smith, Manohara Kenchaiah, Gomathi Margabanthu, Foteini Kavvoura, Chandan Yaliwal, AWAF, Rachel Aitken, Olivia Pearce, Sarah Stollery, Elinor Balch, Hanah Batholomew, Zhara Hashmi, Kathleen M. Gillespie, Vito Lampasona, Alistair J. K. Williams, Anna E. Long   +38 more
wiley   +1 more source

Bone Marrow Pathology in Cold Agglutinin‐Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases

European Journal of Haematology, EarlyView.
ABSTRACT Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia (AIHA). CAD occurs in the context of a small clonal B‐cell lymphoproliferation restricted to blood and/or bone marrow (BM), without overt or extramedullary lymphoma. The WHO‐HAEM5 introduced a description of the CAD‐associated lymphoproliferative disorder (CAD‐LPD) in ...
Anne‐Marie L. Becking, Sophie J. Bernelot Moens, Marie José Kersten, Femke V. M. Mulder, Steven T. Pals, Lianne Koens, Josephine M. I. Vos   +6 more
wiley   +1 more source

Biotechnological Applications of C-Type Lectins Isolated from Snake Venoms

Molecules
Snake venoms are rich sources of molecules with pharmacological potential, with approximately 90% of their composition consisting of proteins and peptides responsible for their biological activities.
Ellynes Amancio Correia Nunes, Geovanna Moura, Breno Emanuel Farias Frihling, Juliana Ferreira de Lima, Adriel Parahyba Lacerda, Rayane Vasconcelos, Ana Paula de Araújo Boleti, Ana Cristina Jacobowski, Juliana Zuliani, Elizeu Antunes dos Santos, Hector Koolen, Karla Luna, Maria Ligia Rodrigues de Macedo, Ludovico Migliolo   +13 more
doaj   +1 more source

Clinical and Genetic Characterization of 269 Patients With Suspected Inherited Platelet Disorders: The Padua Monocentric Experience

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Inherited platelet disorders (IPDs) are rare hematologic conditions encompassing a heterogeneous spectrum of quantitative and qualitative platelet defects, frequently associated with variable clinical phenotypes and comorbidities. Accurate diagnosis necessitates comprehensive genetic characterization, detailed clinical and bleeding ...
Silvia Ferrari, Daniela Regazzo, Antonella Bertomoro, Anna Cerbo, Alessandro Galbiati, Elisabetta Cosi, Paolo Simioni   +6 more
wiley   +1 more source

Yeast Strains as Probiotic and Postbiotic Agents for the Agglutination of Enteric Pathogens: A Preventive Approach

Pathogens
This study evaluates the potential of various yeast strains as probiotic and postbiotic agents for agglutinating enteric pathogens, offering a preventive approach to gastrointestinal infections.
Michelle Cerdán-Alduán, Josune Salvador-Erro, Ana Villegas-Remírez, David García-Yoldi, Ana Ceniceros, Yadira Pastor, Carlos Gamazo   +6 more
doaj   +1 more source

Analytical and Clinical Performance of the Atellica HEMA 580 Haematology Analyzer: A Comparison With the ADVIA 2120i

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The Atellica HEMA 580 is a novel haematology analyser providing eight‐part leukocyte differential and optical platelet (PLT) counting. We compared its analytical and clinical performance with that of the ADVIA 2120i. Methods A total of 796 residual whole blood specimens were analysed.
Hyeongyu Lee, Jooyoung Cho, Gilsung Yoo, Juwon Kim   +3 more
wiley   +1 more source

Meillet’s Grammaticalisation as a Term and Concept: its Historical Foundations and Modern Rediscovery

Histoire Épistémologie Langage
It is generally accepted that Meillet (1912) coined the term grammaticalisation. However, the changes to which this term refers had been the subject of scholarly discussions long before Meillet’s involvement.
Carita Klippi, Therese Lindström Tiedemann   +1 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Production and Characterization of Immune Ascitic Fluids to Vibrio cholerae R-Variant Strains

Проблемы особо опасных инфекций
The aim of the work was to obtain immune ascitic fluids (IAF) of mice to whole cells of R-variant cholera vibrios and to evaluate the possibility of their use for detection and characterization of atypical cholera vibrios. Materials and methods.
V. V. Evdokimova, L. P. Alekseeva, O. A. Yakusheva, D. A. Levchenkо, M. V. Rengach   +4 more
doaj   +1 more source

Intraspecific Variation in the Characteristics of Cryptocaryon irritans Isolated in Japan

Journal of Fish Diseases, EarlyView.
ABSTRACT Cryptocaryon irritans is an obligate parasitic ciliate and the causative agent of cryptocaryoniasis. This parasite is widely distributed in tropical and subtropical marine waters, and numerous outbreaks in aquaculture have been reported worldwide. Previous studies have documented variations in biological traits, such as cell size, serotype and
Hiromi Matsuoka, Toshihide Iwatsuki, Maho Kotake, Tomoki Honryo, Sho Shirakashi, Naoki Itoh, Yuho Watanabe   +6 more
wiley   +1 more source