Results 71 to 80 of about 345,702 (307)

A hierarchical approach to multi-project planning under uncertainty [PDF]

open access: yes, 2004
We survey several viewpoints on the management of the planning complexity of multi-project organisations under uncertainty. A positioning framework is proposed to distinguish between different types of project-driven organisations, which is meant to aid ...
Hans, E.W.   +3 more
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Aggregate Spending and the Terms of Trade: Is There a Laursen-Metzler Effect? [PDF]

open access: yes
This paper investigates the spending and current-account effects of permanent terms-of-trade shifts in a model where households maximize utility over an infinite planning period.
Maurice Obstfeld
core  

Aggregates safeguarding map of Mid Wales (South) [PDF]

open access: yes, 2012
Aggregates Safeguarding Map of Wales - As mineral resources are finite and are not evenly distributed, knowledge about their whereabouts is essential for making effective and sustainable planning decisions that consider the needs of future generations ...

core  

The contribution of ecological footprinting to planning policy development: using REAP to evaluate policies for sustainable housing construction [PDF]

open access: yes, 2008
The complexity of the sustainable-development policy goal is such that policy makers are searching for tools to enable them to evaluate and develop policy directions.
Nye, M, Rydin, Y
core   +1 more source

Multi-objective aggregate production planning with fuzzy parameters

open access: yesAdvances in Engineering Software, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Baykasoglu, Adil, Gocken, Tolunay
openaire   +4 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Perencanaan Produksi Agregat CV XYZ Dengan Jumlah Tenaga Kerja Tetap

open access: yesJurnal Aplikasi Bisnis dan Manajemen, 2020
CV XYZ is a growing plywood company. In increasing the company's competitiveness, CV XYZ seeks to find more ideal production planning for the company.
Fadhillah Fairuzzahira   +2 more
doaj   +1 more source

Water Management and the Valuation of Indirect Environmental Services [PDF]

open access: yes
Comprehensive water basin and watershed planning and management require valuation of the intermediate ecological services provided to the water resources themselves.
Brooks Kaiser, James A Roumasset
core  

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