Results 41 to 50 of about 5,821 (279)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Provably secure certificateless aggregate signature scheme in wireless roaming authentication

Tongxin xuebao, 2017
Certificateless aggregate signature (CLAS) schemes have been widely applied in resource-constrained wireless mobile networks,because they could not only realize batch validation but also solve the certificate management and key escrow problems.It was ...
Zhi-yan XU, Li-bing WU, Li LI, De-biao HE   +3 more
doaj   +2 more sources

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Efficient certificate‐based aggregate signature scheme for vehicular ad hoc networks

IET Networks, 2020
As vehicle speed is fast and on board units' (OBUs) computing power, storage space, bandwidth and other resources are very limited, the efficiency of message transmission in vehicular ad hoc network is of great concern.
Jian‐Neng Chen, Zhen‐Jie Huang, Yu‐Ping Zhou, Fu‐Min Zou, Chien‐Ming Chen, Jimmy Ming‐Tai Wu, Tsu‐Yang Wu   +6 more
doaj   +1 more source

Cryptanalysis and Improvement of Three Certificateless Aggregate Signature Schemes [PDF]

Mathematical Problems in Engineering, 2018
The certificateless aggregate signature (CLAS) scheme is a very important data aggregation technique that compresses a large number of signatures from different users into a short signature. CLAS can reduce the total length of a signature and the computational overhead of signature verification and is therefore highly suitable for resource-constrained ...
Xiaodong Yang, Yutong Li, Chunlin Chen, Likun Xiao, Caifen Wang   +4 more
openaire   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Certificateless Anonymous Authentication Scheme Supporting Illegal Signatures Localization for Internet of Vehicles [PDF]

Jisuanji gongcheng
In the Internet of Vehicles (IoV) environment, vehicles are connected to public networks through the Internet and information is vulnerable to various malicious attacks from attackers during transmission.
YANG Xiaodong, LI Muzi, MA Guozu, LI Songyu, WANG Caifen
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source