Results 51 to 60 of about 78,642 (289)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Visualization of supramolecular assembly by aggregation‐induced emission
Aggregate, 2023 Supramolecular architectures are constructed by the self‐assembly of small building blocks via the use of metal‐ligand coordination, π–π stacking interactions, hydrogen bonding, host‐guest interactions, and other noncovalent driving forces, which confer ...
Wu‐Jie Guo +7 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
A new aggregation induced emission enhancement (AIEE) dye which self-assembles to panchromatic fluorescent flowers and has application in sensing dichromate ions [PDF]
, 2022 Vivekshinh Kshtriya +8 more
openalex +1 more source
Themed Issue on Aggregation‐Induced Emission (AIE) [PDF]
Chemistry – An Asian Journal, 2019 In their editorial to this special issue, guest editors Bin Liu and Ben Zhong Tang provide a brief overview of the history and recent growth in the area of aggregation-induced emission. They furthermore highlight the state-of-the-art contributions in this research field featured in this special issue.
Bin, Liu, Ben Zhong, Tang
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Nature Communications, 2022 Organic materials with both aggregation induced emission (AIE) and aggregation-caused quenching (ACQ) effects that can emit with multiple wavelengths in the solution and aggregated state are rarely reported.
Xinyu Zhang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
AggregateFluorescent lateral flow immunoassay (LFIA) has emerged as a critical point‐of‐care (POC) diagnostic platform for in vitro diagnosis. However, the analytical sensitivity of conventional fluorescent LFIA is constrained by the suboptimal quantum yield (QY)
Yaxin Hu +6 more
doaj +1 more source