Results 51 to 60 of about 752,343 (341)

Should I Say Something? Dating and Sexual Aggression Bystander Intervention Among High School Youth [PDF]

open access: yes, 2015
Using data from a sample of 218 high school youth from three high schools in New England (one rural, two urban), this brief discusses dating and sexual aggression bystander intervention among high school youth. Authors Katie Edwards, Robert Eckstein, and
Eckstein, Robert P   +2 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

A Conceptual Review of Lab-Based Aggression Paradigms

open access: yesCollabra: Psychology, 2018
Aggression is often defined as a behavior that is done with the intent to harm an individual who is believed to want avoid being harmed (e.g., Baron & Richardson, 1994).
Randy J. McCarthy, Malte Elson
doaj   +1 more source

Exploring the Role of Attachment Style in the Relation between Family Aggression and Abuse in Adolescent Dating Relationships [PDF]

open access: yes, 2010
This study investigated romantic attachment style as a potential moderator of the link between family aggression and dating aggression, and examined its relations with documented mediators of the impact of interparental conflict on dating behavior ...
Grych, John H., Kinsfogel, Kristen M.
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Isolation and social instigation in animal models of aggression: effects of an mGLU1 receptor antagonist administration [PDF]

open access: yes, 2017
Isolate-induced aggression in male mice is a model widely used in psychoparmacology of aggression. Animals are usually isolated for 30 days and subsequently treated and confronted with an anosmic opponent in a neutral area.
Martin-Lopez, Maria Mercedes
core  

Differential Effects of Neonatal Testosterone Treatment on Aggression in Two Selection Lines of Mice [PDF]

open access: yes, 1992
Selection lines of mice, artificially selected for aggression based upon the attack latency score (ALS), were used. In order to determine the relative contribution of neonatal testosterone (T) in the development of aggression, we vary the plasma-T level ...
Bohus, Béla,   +4 more
core   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

TYPE 2 DIABETES MELLITUS: A RISK FACTOR OF AGGRESSION IN ADULTS

open access: yesKhyber Medical University Journal, 2021
OBJECTIVE: To examine the problem of aggression (physical aggression, verbal aggression, anger and hostility) among patients with type 2 diabetes mellitus (T2DM) in comparison to normal adults.
Riffat Sadiq   +5 more
doaj   +1 more source

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