Results 1 to 10 of about 12,311,713 (381)
Scientific Reports, 2022 Canine cognitive dysfunction (CCD) is a neurodegenerative disease in aging dogs. It has been described previously in relatively small cohorts of dogs using multiple different rating scales.
Sarah Yarborough +3 more
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Implementation and review of the care ecosystem in an integrated healthcare system
BMC Geriatrics, 2023 Background and objectives The University of California, San Francisco Memory and Aging Center (UCSF-MAC) led the development and tested a collaborative care model delivered by lay care team navigators (CTNs) with support from a multidisciplinary team ...
Michael H. Rosenbloom +10 more
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Coenzyme A binding sites induce proximal acylation across protein families
Scientific Reports, 2023 Lysine Nɛ-acylations, such as acetylation or succinylation, are post-translational modifications that regulate protein function. In mitochondria, lysine acylation is predominantly non-enzymatic, and only a specific subset of the proteome is acylated ...
Chris Carrico +8 more
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Impact of atrial fibrillation on the cognitive decline in Alzheimer’s disease
Alzheimer’s Research & Therapy, 2023 Background Atrial fibrillation (AF) is a strong risk factor for Alzheimer’s disease (AD) independent of ischemic stroke. However, the clinicopathological impact of AF on the severity of AD has not been well elucidated.
Taizen Nakase +8 more
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Nature Communications, 2021 The serine protease TMPRSS2 primes SARS-CoV-2 glycoprotein for cell entry. Here, the authors perform a screen to identify drugs that reduce TMPRSS2 expression and find that halofuginone modulates proteasome-mediated degradation of TMPRSS2 and reduces ...
Yanwen Chen +16 more
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Expert consensus on neuroimaging diagnosis of dementia and cognitive impairment (2023) [PDF]
Zhenduanxue lilun yu shijianFor patients with cognitive impairment as the main clinical manifestation, structural MRI (or CT instead) should be performed first to clarify intracranial lesions and brain atrophy.
Aging and Cognitive Impairment Branch of Shanghai Society of Aging and Degenerative Diseases
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Brain Stimulation, 2021 Background: Repetitive Transcranial Magnetic Stimulation (rTMS) has shown initial promise in combating age-related cognitive decline and dementia. The nature and severity of cognitive aging, however, varies markedly between individuals.
Marina Weiler +6 more
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, 2001 We derive exact expressions for a number of aging functions that are scaling limits of non-equilibrium correlations, R(tw,tw+t) as tw --> infinity with t/tw --> theta, in the 1D homogenous q-state Potts model for all q with T=0 dynamics following a ...
A. J. Bray +28 more
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Korean Journal of Audiology, 2013 Aging is initiated based on genetic and environmental factors that operate from the time of birth of organisms. Aging induces physiological phenomena such as reduction of cell counts, deterioration of tissue proteins, tissue atrophy, a decrease of the metabolic rate, reduction of body fluids, and calcium metabolism abnormalities, with final progression
Park, Dong Choon, Yeo, Seung Geun
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Aging Scaled Brownian Motion [PDF]
, 2015 Scaled Brownian motion (SBM) is widely used to model anomalous diffusion of passive tracers in complex and biological systems. It is a highly non-stationary process governed by the Langevin equation for Brownian motion, however, with a power-law time ...
Chechkin, A. V. +3 more
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