Results 261 to 270 of about 237,133 (291)
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2012
Cockayne Syndrome – De Barsy Syndrome – Hallermann-Streiff Syndrome – Hutchinson-Gilford Progeria – Werner ...
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Cockayne Syndrome – De Barsy Syndrome – Hallermann-Streiff Syndrome – Hutchinson-Gilford Progeria – Werner ...
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Science, 2018
Premature Aging Cells from patients with Hutchinson-Gilford progeria syndrome (HGPS) have defects in nuclear architecture that lead to premature cellular senescence. Larrieu et al. investigated the mechanisms by which a small molecule called remodelin improves the phenotype of HGPS cells (see the Focus by Wilson).
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Premature Aging Cells from patients with Hutchinson-Gilford progeria syndrome (HGPS) have defects in nuclear architecture that lead to premature cellular senescence. Larrieu et al. investigated the mechanisms by which a small molecule called remodelin improves the phenotype of HGPS cells (see the Focus by Wilson).
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Growth Hormone and Premature Ageing
Nature, 1973IT has often been suggested that the immune system may be involved in ageing1–4 Fabris et al.5 claim that such immune deficiencies are caused by inadequate stimulation of the lymphoid system by growth hormone (GH). They compared mice with inherited pituitary dwarfism (homozygotes for Snell's dwarf mutation, dw) with normal mice from the same stock. The
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Transcription-coupled repair and premature ageing
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005During the past decades, several cellular pathways have been discovered to be connected with the ageing process. These pathways, which either suppress or enhance the ageing process, include regulation of the insulin/growth hormone axis, pathways involved with caloric restriction, ROS metabolism and DNA repair.
Andressoo, JO (Jaan-Olle) +1 more
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Human Premature Aging Diseases
2007A number of rare human disorders are associated with distinct clinical features that resemble the aging process at an early stage in life. The study of these conditions has greatly advanced our insight into the aging process. Here, we discuss the clinical and molecular characteristics as well as the recent advances in our insight into the mechanisms of
Dai-Di Gan +3 more
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Premature Aging Gene Discovered
Science, 1996Patients who have the rare hereditary condition known as Werner's syndrome begin aging dramatically while still in their twenties. Their hair goes gray, their skin loses its suppleness, and worse, they also develop cancer, heart disease, and many other diseases that usually don't strike until later in life. On page 258
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Aging of Premature-Aging Syndrome Cells
2003Natural aging is regarded as the gradual deterioration of body functions throughout the lifetime of an individual. The aging process results from a contribution of genetic factors as well as environmental agents acting on the organism since the time of conception.
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Understanding Premature Skin Aging
New England Journal of Medicine, 1997Dermatologists see many patients seeking help because of skin aging. Sagging and wrinkling of the skin can be the signs of time spent on the beach in younger years or on the golf course in middle y...
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