Results 151 to 160 of about 1,760,131 (304)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

mRNA Therapeutics for Skin Rejuvenation: From Aging Atlases to Clinical Translation. [PDF]

Exp Dermatol
Boncimino F, Sol S, Todorova K, Mandinova A.   +3 more
europepmc   +1 more source

Other title: Aging and Disabilities Resource Center Overview

, 2017
April 19, 2017. Date and committee name taken from Kansas Department for Aging and Disability Services website.; Information provided to the Kansas Legislature, Robert G. Bethell Joint Committee, by the Kansas Department for Aging and Disability Services.
Kansas. Department for Aging and Disability Services.
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Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Traditional Chinese Medicine Formulas in Delaying Aging: From Theoretical Foundations to Molecular Mechanisms and Translational Perspectives. [PDF]

J Cell Mol Med
Jin C, Du D, Yu X, Ji X, Zhang X, Li A, Zu S, Qu B, Zhao D, Wu D, Liu M.   +10 more
europepmc   +1 more source

Double Jeopardy Project summary of focus group results.

, 2002
Title from title screen.; Harvested from the web on 9/4/02Summarizes the results of focus groups conducted to support the "Double Jeopardy" project: supporting families in planning for a secure future for their adult children with developmental ...
Ohio.Dept. of Aging.
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Unconventional animal models of Alzheimer's disease and aging: key insights from the UAMAA 2026 conference. [PDF]

Lab Anim (NY)
Garduño BM, Melgarejo T, Cogram P, Holmes TC, Xu X.   +4 more
europepmc   +1 more source

Other title: Kansas Department for Aging and Disability Services Overview; Other title: Overview

, 2018
application/pdf; "1/11/2018."; Committee name taken from Kansas Department for Aging and Disability Services website.; Presentation before the Kansas Legislature, House Children and Seniors Committee, by the Kansas Department for Aging and Disability ...
Kansas. Department for Aging and Disability Services.
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Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source