Results 11 to 20 of about 2,225,048 (294)
MARK-AGE biomarkers of ageing [PDF]
Mechanisms of Ageing and Development, 2015 Many candidate biomarkers of human ageing have been proposed in the scientific literature but in all cases their variability in cross-sectional studies is considerable, and therefore no single measurement has proven to serve a useful marker to determine, on its own, biological age.
Bürkle, Alexander +29 more
openaire +6 more sources
Proceedings of the Royal Society of London. Series B: Biological Sciences, 2004 According to the antagonistic pleiotropy theory of ageing, natural selection has favoured genes conferring short-term benefits to the organism at the cost of deterioration in later life. The 'disposable soma' theory expresses this as a life-history strategy in which somatic maintenance is below the level required to prevent ageing, thus enabling higher
Robert M. Seymour, Peter D. Sozou
openaire +4 more sources
The future of Age and Ageing [PDF]
Age and Ageing, 2002 The delivery of healthcare in the United Kingdom is going through a period of change, with many new developments. Some of these represent the aspirations of politicians and those who manage the National Health Service, and others are being forced upon us because of the shortage of resources (not always financial).
openaire +3 more sources
Ageing and vascular ageing [PDF]
Postgraduate Medical Journal, 2006 Abstract There is an age related decline in various physiological processes. Vascular ageing is associated with changes in the mechanical and the structural properties of the vascular wall, which leads to the loss of arterial elasticity and reduced arterial compliance.
B Jani, C Rajkumar
openaire +3 more sources
Age and Ageing: An Overview [PDF]
Occupational Medicine, 2000 Europe is ageing, as exemplified by the UK population where, in the foreseeable future, more people will be over than under age 50: industry appears slow to recognise and appreciate all that older workers still have to offer: bundling them off into early retirement wastes precious talents. Memory difficulty is not an inevitable part of ageing.
openaire +2 more sources
Korean Journal of Audiology, 2013 Aging is initiated based on genetic and environmental factors that operate from the time of birth of organisms. Aging induces physiological phenomena such as reduction of cell counts, deterioration of tissue proteins, tissue atrophy, a decrease of the metabolic rate, reduction of body fluids, and calcium metabolism abnormalities, with final progression
Park, Dong Choon, Yeo, Seung Geun
openaire +2 more sources
A role for worm cutl-24 in background- and parent-of-origin-dependent ER stress resistance
BMC Genomics, 2022 Background Organisms in the wild can acquire disease- and stress-resistance traits that outstrip the programs endogenous to humans. Finding the molecular basis of such natural resistance characters is a key goal of evolutionary genetics.
Wenke Wang +4 more
doaj +1 more source
Lipids in Health and Disease, 2018 Background Accumulating evidences have shown that miRNAs are directly or indirectly involved in a variety of biological processes, and closely associated with diverse human diseases, including cardiovascular diseases.
Meng-yun Cai +8 more
doaj +1 more source
BMC Geriatrics, 2018 Background Peripheral sensory loss is considered one of many risk factors for gait impairments and falls in older adults, yet no prospective studies have examined changes in touch sensation in the foot over time and their relationship to mobility and ...
Lewis A. Lipsitz +5 more
doaj +1 more source
Journal of Biomedical Science, 2022 Background Patients with colon adenocarcinoma (COAD) exhibit significant heterogeneity in overall survival. The current tumor-node-metastasis staging system is insufficient to provide a precise prediction for prognosis.
Jing Lu +8 more
doaj +1 more source