Results 61 to 70 of about 583,540 (283)

Three minutes propofol after sevoflurane anesthesia to prevent emergence agitation following inguinal hernia repair in children: a randomized controlled trial [PDF]

Korean Journal of Anesthesiology, 2019
Background Emergence agitation (EA) is a common problem after sevoflurane anesthesia among children. There have been mixed results with control of EA using propofol 1 mg/kg bolus following sevoflurane anesthesia. An infusion of 3 mg/kg of propofol over 3
Mostafa Samy Abbas, Essam Ezzat Abd El-Hakeem, Hossam Esmat Kamel   +2 more
doaj   +1 more source

Synergistic Effects of Stirring and Aeration Rate on Carotenoid Production in Yeast Rhodotorula toruloides CCT 7815 Envisioning Their Application as Soap Additives

Fermentation, 2023
The production of carotenoids by microbial organisms has gained significant interest due to the growing demand for natural products. Among the non-model oleaginous red yeasts, Rhodotorula toruloides stands out as an appealing host for natural carotenoid ...
Renata M. M. G. P. Ribeiro, Bruno W. Picão, Daniele O. Gonçalves, Mateus Scontri, Vitor T. Mazziero, Cassamo U. Mussagy, Vijaya Raghavan, Carolina Astudillo-Castro, Andrés Córdova, Marcel O. Cerri, Elias B. Tambourgi   +10 more
doaj   +1 more source

Genes of the serotonergic and dopaminergic pathways and their interaction affect the expression of Behavioural and Psychological Symptoms in Dementia (BPSD). [PDF]

, 2009
Although there is evidence for the involvement of genes of serotonergic and dopaminergic systems in the manifestation of the Behavioural and Psychological Symptoms in Dementia (BPSD), genetic association studies are contradictory.
Belinda Martin, Brian Lawlord, Gillian Hamilton, John Powell, Julie Williams, Michael Gill, Michael J. Owen, Michelle Lupton, Nicola Archer, Paul hollingworth, Petroula Proitsi, Simon Lovestone, Suzanne Reeves   +12 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Agitation and impulsivity in mid and late life as possible risk markers for incident dementia

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2020
To identify knowledge gaps regarding new‐onset agitation and impulsivity prior to onset of cognitive impairment or dementia the International Society to Advance Alzheimer's Research and Treatment Neuropsychiatric Syndromes (NPS) Professional Interest ...
Daniel R. Bateman, Sascha Gill, Sophie Hu, Erin D. Foster, Myuri T. Ruthirakuhan, Allis F. Sellek, Moyra E. Mortby, Veronika Matušková, Kok Pin Ng, Rawan M. Tarawneh, Yvonne Freund‐Levi, Sanjeev Kumar, Serge Gauthier, Paul B. Rosenberg, Fabricio Ferreira de Oliveira, D. P. Devanand, Clive Ballard, Zahinoor Ismail, for The International Society to Advance Alzheimer's Research and Treatment (ISTAART), Neuropsychiatric Syndromes Professional Interest Area (NPS‐PIA)   +18 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Improved extraction technique for biological fluids [PDF]

, 1975
Liquid-liquid extraction technique speeds up separation of biological fluids into number of compounds. This eliminates agitation, emulsion formation, centrifugation, mechanical separation of phases, filtration, and other steps that have been used ...
Jahnsen, V. J.
core   +1 more source

Megasonic Enhanced Electrodeposition [PDF]

, 2008
A novel way of filling high aspect ratio vertical interconnection (microvias) with an aspect ratio of >2:1 is presented. High frequency acoustic streaming at megasonic frequencies enables the decrease of the Nernst-diffusion layer down to the sub-micron ...
Desmulliez, Marc, Kaufmann, Jens Georg, Price, D.   +2 more
core   +5 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source