Results 131 to 137 of about 19,284 (137)
Some of the next articles are maybe not open access.
Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas
Virchows Archiv, 2011The pathogenesis of colorectal carcinoma (CRC) is a complex process that involves the recruitment of both genetic and epigenetic mechanisms. Recent studies underline the cardinal role of small, noncoding RNA molecules, called microRNAs (miRs), in the pathobiology of numerous physiological and pathological processes, including oncogenesis.
Angeliki Korpetinou +7 more
openaire +3 more sources
The Role of Ago2 in microRNA Biogenesis: An Investigation of miR-21
2015Research into the biology of microRNAs (miRNA) continues to expand rapidly. As a result, their abundance and importance in cellular regulation and disease states, also continues to grow and they are considered master regulators. Despite this greater understanding, key mechanisms regulating global miRNA transcription have remained elusive.
Charles C. King +3 more
openaire +2 more sources
Understanding Assembly of AGO2 RISC: the RNAi enzyme: a Dissertation
2007In 1990, Richard Jorgensen’s lab initiated a study to test if they could create a more vivid color petunia (Napoli et al. 1990). Their plan was to transform plants with the chalcone synthase transgene––the predicted rate limiting factor in the production of purple pigmentation.
openaire +3 more sources
Identifying RISC Components Using Ago2 Immunoprecipitation and Mass Spectrometry
2017Complex immunoprecipitation (Co-IP) is a powerful technique for precipitating an intact protein complex out of solution and cell lysates using an antibody that specifically binds to a particular protein in a large complex of proteins. Mass spectrometry (MS) is used to identify, sequence, and quantify proteins.
openaire +3 more sources
Viroid resistance conferred by AGO2 in transgenic tomato plants: Viroids or AGO2, who wins?
ASPB PLANT BIOLOGY 2020, 2020openaire +1 more source
AGO2 localizes to the nucleus in quiescence and represses transposon expression
Nature Structural & Molecular Biology, 2023openaire +2 more sources
Enhanced RNAi efficiency of silkworm through overexpression of Ago2
2016 International Congress of Entomology, 2016openaire +2 more sources