Results 1 to 10 of about 24,859 (201)
Argonaute and Argonaute-Bound Small RNAs in Stem Cells [PDF]
International Journal of Molecular Sciences, 2016 Small RNAs are essential for a variety of cellular functions. Argonaute (AGO) proteins are associated with all of the different classes of small RNAs, and are indispensable in small RNA-mediated regulatory pathways. AGO proteins have been identified in various types of stem cells in diverse species from plants and animals.
Zhai Lihong, Xiao Juan
exaly +5 more sources
A Prokaryotic Twist on Argonaute Function
Life, 2015 Argonaute proteins can be found in all three domains of life. In eukaryotic organisms, Argonaute is, as the functional core of the RNA-silencing machinery, critically involved in the regulation of gene expression.
Dina Grohmann +2 more
exaly +3 more sources
Biomolecules, 2022 Prokaryotic Argonautes (pAgos) from mesophilic bacteria are attracting increasing attention for their genome editing potential. So far, it has been reported that KmAgo from Kurthia massiliensis can utilize DNA and RNA guide of any sequence to effectively
Xiaoman Jiang +3 more
doaj +1 more source
Barley Anther and Meiocyte Transcriptome Dynamics in Meiotic Prophase I
Frontiers in Plant Science, 2021 In flowering plants, successful germinal cell development and meiotic recombination depend upon a combination of environmental and genetic factors. To gain insights into this specialized reproductive development program we used short- and long-read RNA ...
Abdellah Barakate +13 more
doaj +1 more source
RNA interference of Aspergillus flavus in response to Aspergillus flavus partitivirus 1 infection
Frontiers in Microbiology, 2023 RNA interference (RNAi) is one of the important defense responses against viral infection, but its mechanism and impact remain unclear in mycovirus infections.
Yinhui Jiang +17 more
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Understanding miRNA Based Gene Regulation in Parkinson’s Disease: An in silico Approach [PDF]
International Journal Bioautomation, 2020 Parkinson’s disease (PD) is the second most common neurodegenerative disorder, mainly characterized by depletion or insufficient release of dopaminergic neurons in substantia nigra of the midbrain.
Surya Narayan Rath, Manorama Patri
doaj +1 more source
eLife, 2022 MicroRNAs (miRNAs), in association with Argonaute (AGO) proteins, direct repression by pairing to sites within mRNAs. Compared to pairing preferences of the miRNA seed region (nucleotides 2–8), preferences of the miRNA 3′ region are poorly understood ...
Sean E McGeary +4 more
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Targeting Argonaute to chromatin [PDF]
Genes & Development, 2016 In many eukaryotes, siRNAs bound to Argonaute proteins guide chromatin-modifying enzymes to complementary loci, resulting in transcriptional gene silencing. Multiple lines of evidence indicate that siRNAs base-pair with longer RNAs produced at target loci, but the possibility that siRNAs base-pair directly with DNA remains an attractive hypothesis.
Wendte, Jered M., Pikaard, Craig S.
openaire +2 more sources
The Argonaute protein family [PDF]
Genome Biology, 2008 Argonaute proteins were first discovered genetically, and extensive research in the past few years has revealed that members of the Argonaute protein family are key players in gene-silencing pathways guided by small RNAs. Small RNAs such as short interfering RNAs (siRNAs), microRNAs (miRNAs) or Piwi-interacting RNAs (piRNAs) are anchored into specific ...
Höck, J., Meister, G.
openaire +3 more sources
Plants, 2019 Competing endogenous RNAs (ceRNAs) are natural transcripts that can act as endogenous sponges of microRNAs (miRNAs), modulating miRNA action upon target mRNAs. Circular RNAs (circRNAs) are one among the various classes of ceRNAs. They are produced from a
Érika Frydrych Capelari +3 more
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