Results 1 to 10 of about 30,324 (235)

A Prokaryotic Twist on Argonaute Function

Life, 2015
Argonaute proteins can be found in all three domains of life. In eukaryotic organisms, Argonaute is, as the functional core of the RNA-silencing machinery, critically involved in the regulation of gene expression.
Sarah Willkomm, Dina Grohmann
exaly   +4 more sources

Emerging Argonaute-based food safety detection: from amplification to amplification-free manner [PDF]

Frontiers in Microbiology
Food safety has attracted extensive global attention, making the development of efficient and rapid detection methods essential for food safety risk control. Argonaute-based biosensing has emerged as a promising tool for food safety analysis owing to its
Wen Kang, Yaru Li, Lu Zhao, Long Ma, Yunfeng Bai, Yunfeng Bai, Feng Feng   +6 more
doaj   +2 more sources

Argonaute 2 stabilization of microRNAs controls adult neurogenesis and oligodendrogenesis [PDF]

Neural Regeneration Research
MicroRNAs regulate neural stem cell function. Argonaute 2 protein, constituent of the RNA-induced silencing complex, plays an important role in regulating microRNA function for post-transcriptional gene silencing.
Xianshuang Liu, Wanlong Pan, Michael Chopp, Baoyan Fan, Xinli Wang, Julie Landschoot-Ward, Min Wei, Qinge Lu, Helen Liu, William Golembieski, Sutapa Santra, Zheng Gang Zhang   +11 more
doaj   +2 more sources

Characterization of a Programmable Argonaute Nuclease from the Mesophilic Bacterium Rummeliibacillus suwonensis

Biomolecules, 2022
Prokaryotic Argonautes (pAgos) from mesophilic bacteria are attracting increasing attention for their genome editing potential. So far, it has been reported that KmAgo from Kurthia massiliensis can utilize DNA and RNA guide of any sequence to effectively
Xiaoman Jiang, Yang Liu, Qi Liu, Lixin Ma   +3 more
doaj   +1 more source

Barley Anther and Meiocyte Transcriptome Dynamics in Meiotic Prophase I

Frontiers in Plant Science, 2021
In flowering plants, successful germinal cell development and meiotic recombination depend upon a combination of environmental and genetic factors. To gain insights into this specialized reproductive development program we used short- and long-read RNA ...
Abdellah Barakate, Jamie Orr, Miriam Schreiber, Isabelle Colas, Dominika Lewandowska, Nicola McCallum, Malcolm Macaulay, Jenny Morris, Mikel Arrieta, Pete E. Hedley, Luke Ramsay, Robbie Waugh, Robbie Waugh, Robbie Waugh   +13 more
doaj   +1 more source

RNA interference of Aspergillus flavus in response to Aspergillus flavus partitivirus 1 infection

Frontiers in Microbiology, 2023
RNA interference (RNAi) is one of the important defense responses against viral infection, but its mechanism and impact remain unclear in mycovirus infections.
Yinhui Jiang, Yinhui Jiang, Xiang Liu, Xiang Liu, Xun Tian, Xun Tian, Jianhong Zhou, Jianhong Zhou, Qinrong Wang, Qinrong Wang, Bi Wang, Bi Wang, Wenfeng Yu, Wenfeng Yu, Yanping Jiang, Tom Hsiang, Xiaolan Qi, Xiaolan Qi   +17 more
doaj   +1 more source

Understanding miRNA Based Gene Regulation in Parkinson’s Disease: An in silico Approach [PDF]

International Journal Bioautomation, 2020
Parkinson’s disease (PD) is the second most common neurodegenerative disorder, mainly characterized by depletion or insufficient release of dopaminergic neurons in substantia nigra of the midbrain.
Surya Narayan Rath, Manorama Patri
doaj   +1 more source

MicroRNA 3′-compensatory pairing occurs through two binding modes, with affinity shaped by nucleotide identity and position

eLife, 2022
MicroRNAs (miRNAs), in association with Argonaute (AGO) proteins, direct repression by pairing to sites within mRNAs. Compared to pairing preferences of the miRNA seed region (nucleotides 2–8), preferences of the miRNA 3′ region are poorly understood ...
Sean E McGeary, Namita Bisaria, Thy M Pham, Peter Y Wang, David P Bartel   +4 more
doaj   +1 more source

Circular and Micro RNAs from Arabidopsis thaliana Flowers Are Simultaneously Isolated from AGO-IP Libraries

Plants, 2019
Competing endogenous RNAs (ceRNAs) are natural transcripts that can act as endogenous sponges of microRNAs (miRNAs), modulating miRNA action upon target mRNAs. Circular RNAs (circRNAs) are one among the various classes of ceRNAs. They are produced from a
Érika Frydrych Capelari, Guilherme Cordenonsi da Fonseca, Frank Guzman, Rogerio Margis   +3 more
doaj   +1 more source

Inducible and reversible inhibition of miRNA-mediated gene repression in vivo

eLife, 2021
Although virtually all gene networks are predicted to be controlled by miRNAs, the contribution of this important layer of gene regulation to tissue homeostasis in adult animals remains unclear.
Gaspare La Rocca, Bryan King, Bing Shui, Xiaoyi Li, Minsi Zhang, Kemal M Akat, Paul Ogrodowski, Chiara Mastroleo, Kevin Chen, Vincenzo Cavalieri, Yilun Ma, Viviana Anelli, Doron Betel, Joana Vidigal, Thomas Tuschl, Gunter Meister, Craig B Thompson, Tullia Lindsten, Kevin Haigis, Andrea Ventura   +19 more
doaj   +1 more source