Results 141 to 150 of about 1,168,781 (390)
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi+8 more
wiley +1 more source
Corrigendum: A TNFR2-specific TNF fusion protein with improved in vivo activity
Juan Gamboa Vargas+20 more
doaj +1 more source
The muscarinic receptor of heart cell membranes Association with agonists, antagonists and antiarrhythmic agents [PDF]
Daniel Cavey+2 more
openalex +1 more source
Structure and Function of an Irreversible Agonist-β2 Adrenoceptor complex
G-protein-coupled receptors (GPCRs) are eukaryotic integral membrane proteins that modulate biological function by initiating cellular signalling in response to chemically diverse agonists.
D. Rosenbaum+17 more
semanticscholar +1 more source
Pharmacogenetics of β2-Agonists
Short-acting β2-agonists (SABAs) and long-acting β2-agonists (LABAs) are both important for treatment of asthma and chronic obstructive pulmonary disease (COPD) because of their bronchodilator and bronchoprotective effects. However, the use of these agonists, at least for asthma, has generated some controversy because of their association with ...
openaire +4 more sources
This novel 3D human ischemic heart‐on‐a‐chip, with perfusable vasculature directly interfaced with myocardial tissue, replicates key aspects of ischemic heart injury. It also demonstrates the targeted delivery and therapeutic efficacy of cardiac homing peptide‐conjugated liposomes, validating the platform for drug and nanomedicine screening in ...
Junyoung Kim+14 more
wiley +1 more source
Many bacteria use quorum sensing (QS) as an intercellular signaling mechanism to regulate gene expression in local populations. Plant and algal hosts, in turn, secrete compounds that mimic bacterial QS signals, allowing these hosts to manipulate QS ...
Sathish Rajamani+8 more
doaj +1 more source
THE EFFECTS OF H1- AND H2-RECEPTOR AGONISTS AND ANTAGONISTS ON TOTAL LUNG RESISTANCE, DYNAMIC LUNG COMPLIANCE AND IRRITANT RECEPTOR DISCHARGE IN THE ANAESTHETIZED DOG [PDF]
M Dixon, D M Jackson, I M Richards
openalex +1 more source
DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding+5 more
wiley +1 more source
Rat adipocyte β‐adrenergic receptors: evidence in favour of the heterogeneity of agonist‐binding sites and against negatively cooperative interactions [PDF]
Yves Giudicelli+2 more
openalex +1 more source