Results 231 to 240 of about 847,478 (341)

Changes in alpha2 adrenoreceptors in various areas of the rat brain after long-term administration of “mu” and “kappa” opiate agonists [PDF]

, 1983
Charles B. Smith, Peggie J. Hollingsworth, Joann J. Geer, Hylan C. Moises   +3 more
openalex   +1 more source

Global Motor System Suppression as the Primary Mechanism of Human Action Stopping: Challenging the Pause-Then-Cancel Model. [PDF]

J Neurosci
Chaudhuri ER, Long T, Hannah R.
europepmc   +1 more source

Constitutive Androstane Receptor in Macrophages Regulates Toll‐Like Receptor 4‐Mediated Innate Immune Responses Against Endotoxemic Liver Injury

Advanced Science, EarlyView.
The present study uncovers a novel role of constitutive androstane receptor (CAR) in inflammation‐mediated damage. CAR activation in macrophages inhibits proinflammatory macrophages by interacting with Tlr4, which protects against endotoxemic liver injury.
Renjie Cao, Tingting Zhao, Ying Wang, Shaofei Song, Yuan Li, Mengling Hou, Yanxin Zhang, Sengpeng Wong, Siqi Wang, Yuran Wang, Hong Peng, Min Huang, Yiming Jiang   +12 more
wiley   +1 more source

Amelioration of Experimental Amnesia (Passive Avoidance Failure) in Rodents by the Selective M1 Agonist AF102B

, 1988
Noboru Nakahara, Yoshinori Iga, Fumio Mizobe, Gosei Kawanishi   +3 more
openalex   +1 more source

Toll-like receptor 7/8 agonist stimulation rapidly skews the antibody repertoire of B cells in non-human primates. [PDF]

Front Immunol
Wang S, Citron M, Luo L, Wang IM, Liu X, Zhang W.   +5 more
europepmc   +1 more source

Organoid Modeling of Mouse Anterior Tongue Epithelium Reveals Regional and Cellular Identities

Advanced Science, EarlyView.
The tongue's anterior epithelium is maintained by region‐specific stem/progenitor cells, yet in vitro models are limited. Long‐term expanding organoids are developed from adult mouse anterior tongue that retain region‐specific identity, cellular diversity, and gene regulatory features. These organoids differentiate into keratinocytes, Merkel‐like cells,
Seok‐Young Kim, Laurens H. G. Verweij, Lin Lin, Johan H. van Es, Jay Slack, Chris Winkel, Tito Candelli, Philip Lijnzaad, Thanasis Margaritis, Gerben E. Breimer, Karin Sanders, Marc van de Wetering, Hans Clevers   +12 more
wiley   +1 more source

Relative Impact of GLP-1 Agonist Use on Microvascular Versus Macrovascular Complications. [PDF]

Cureus
Okorigba EM, Jinadu KH, Utuk OJ, Akinwumiju A, Kolawole OA, Disu F, Sosu V.   +6 more
europepmc   +1 more source

RIPK1 Drives JAK1‐STAT3 Signaling to Promote CXCL1‐Mediated Neutrophil Recruitment in Sepsis‐Induced Lung Injury

Advanced Science, EarlyView.
This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun, Xiya Li, Shenjia Gao, Yi Jiang, Xinyi Wu, Zhaoyuan Chen, Han Wu, Qing Hua, Rui Zu, Huaijiang Xiang, Ronen Ben‐Ami, Changhong Miao, Li Tan, Ying Li, Jun Wang, Wankun Chen   +15 more
wiley   +1 more source

The neuroleptic-like peptide desenkephalin-γ-endorphin does not antagonize the dopamine receptor agonist-induced inhibition of the release of [3H]dopamine from rat nucleus accumbens slices in vitro [PDF]

, 1987
F.S. Radhakishun, J.C. Stoof, A.H. Mulder, D.H.G. Versteeg, Jan M. van Ree   +4 more
openalex   +1 more source

Current Perspectives on GLP-1 Agonists in Contemporary Clinical Practice from Science and Mechanistic Foundations To Optimal Translation. [PDF]

Curr Atheroscler Rep
Abu-Nejim H, Becker RC.
europepmc   +1 more source