Results 231 to 240 of about 588,311 (310)

A Biofabricated Human Acinus‐on‐a‐Chip Unveils Mechanotransductive Drivers of Ventilator‐Induced Lung Injury via Decoupling Volutrauma and Barotrauma

Advanced Science, EarlyView.
This bioinspired acinus‐on‐a‐chip recapitulates VILI pathology, revealing that volutrauma drives P53/NF‐κB pathways while barotrauma triggers mitochondrial‐Wnt dysregulation. A fibrotic transitional cell cluster was identified. Pharmacological interventions targeting these pathways significantly ameliorated injury, establishing a mechanobiological ...
Heng Lu, Liansheng Liu, Zengyong Hu, Shuxian Fang, Ruohan Ren, Sidi Liu, Meng Zhao, Zhiting Luo, Ziyue Zhang, Wenlong Shao, Qian Liu   +10 more
wiley   +1 more source

RELATIVE POTENCY OF AGONIST AND PARTIAL AGONIST OPIOIDS

British Journal of Anaesthesia, 1985
openaire   +2 more sources

Structural adaptation associated with signaling preference at the human Growth Hormone-Releasing Hormone Receptor. [PDF]

Protein Cell
Wang MW, Hang K, Qiu Y, Chen X, Chen Y, Huang S, Cong Z, Zhou Q.   +7 more
europepmc   +1 more source

Oxidized phosphatidylcholines inhibit airway smooth muscle β2-adrenergic receptors via protein kinase C. [PDF]

Am J Respir Cell Mol Biol
Vaghasiya J, Sikarwar A, Dalvand A, Basu S, Bagan A, Varghese N, Duaqui AA, Pandey D, Mishra S, Ravandi A, Pascoe CD, Halayko AJ, Canadian Respiratory Research Network.   +12 more
europepmc   +1 more source

GLP-1 and GIP class drugs have neuroprotective properties in Alzheimer's and Parkinson's disease. [PDF]

Front Neurosci
Hölscher C.
europepmc   +1 more source