Results 111 to 120 of about 5,919,808 (365)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Challenges of Digital Twin System

Acta Technica Jaurinensis, 2019
Today’s manufacturing and assembly systems have to be flexible to adapt quickly to an increasing number and variety of products. The Industry 4.0 conceptualization has several potentials, i.e.
Cristina Rosaria Monsone, János Jósvai
doaj   +1 more source

The ASSISTANT project: AI for high level decisions in manufacturing

, 2022
Gabriel G. Castañé, Alexandre Dolgui, Niki Kousi, Bart Meyers, Simon Thevenin, Eduardo Vyhmeister, P-O. Östberg   +6 more
openalex   +2 more sources

When AI meets AI: analyzing AI bills using AI

AI & SOCIETY
Abstract With the rapid advancement of Artificial Intelligence (AI) technology and its pervasive integration into society, governments worldwide have introduced a range of AI-related policies. In the United States, the use of AI technology has surged significantly since 2021, driven by the emergence of generative AI and its transformative ...
openaire   +1 more source

A multimodal generative AI copilot for human pathology

Nature
Computational pathology1,2 has witnessed considerable progress in the development of both task-specific predictive models and task-agnostic self-supervised vision encoders3,4.
Ming Y. Lu, Bowen Chen, Drew F. K. Williamson, Richard J. Chen, Melissa Zhao, Aaron K Chow, Kenji Ikemura, Ahrong Kim, Dimitra Pouli, Ankush U Patel, Amr Soliman, Chengkuan Chen, Tong Ding, Judy J. Wang, Georg K. Gerber, Ivy Liang, L. Le, Anil V. Parwani, Luca L. Weishaupt, Faisal Mahmood   +19 more
semanticscholar   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

What Links Retail to Modernity? The Future of Retail - Romanian Case Study A combined Analysis of Consumer Perceptions and AI Insights

Romanian Economic Journal
This study examines the link between retail and modernity and bring as case study the Romanian perception of the future of the store. The research combines insights from secondary data consumer perception study with the potential applications of AI ...
Andreea Strătilă (Irimia)
doaj   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Can and Should AI Help Us Quantify Philosophical Health?

Open Philosophy
We explore the potential and limitations of using artificial intelligence to quantify philosophical health. Philosophical health is an approach to well-being defined as the dynamic coherence between thoughts, values, and actions in harmony with the world.
de Miranda Luis
doaj   +1 more source

The Society of Remote Control: AI and Other Intelligences

Anglica. An International Journal of English Studies
The paper reads the power of social media, especially Artificial Intelligence, in the light of Foucault, and Benjamin, and, especially, Deleuze, on the society of control, as he calls it: to which this paper adds the word “remote” since this quality is ...
Jeremy Tambling
doaj   +1 more source