Results 111 to 120 of about 2,464,013 (361)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

A magnitude da infecção pelo HIV-Aids em maiores de 50 anos no Município de Fortaleza-CE

open access: yesDST, 2004
Introdução: atualmente, têm-se percebido mudanças no curso da epidemia da aids, e uma delas é o aumento do número de casos na faixa etária de 50 a 70 anos, o que vem demonstrar a exclusão deste grupo nos projetos e programas de educação e prevenção do ...
Aline R. Feitoza   +2 more
doaj  

The prevalence of syphilis in HIV-seropositive patients: a retrospective study at the regional hospital in Agadir, Morocco

open access: yesThe Pan African Medical Journal, 2019
INTRODUCTION: HIV and syphilis are major public health problems in Morocco. The region of Souss-Massa, south-west of the country, hold more than 24% of HIV seropositive cases registered in Morocco during 2009.
Mohamed Bourouache   +9 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

HIV And The Need For A Voluntarist Approach [PDF]

open access: yes, 1992
After a decade of fighting AIDS, the public health community has come to recognize that strategies to combat the infection must be premised on voluntarism and not on coercion.
Hansell, Esq., David A.
core   +1 more source

Erotismo e prevenção de DST/Aids entre os adolescentes

open access: yesDST, 2005
Introdução: os meios de comunicação têm tido uma participação cada vez mais frequente e intensa nas pessoas, principalmente nos jovens, mas nãose tem conhecimento de que tipo de informação sobre erotização e prevenção de DST/Aids está sendo passada aos ...
Glauco R Mello   +3 more
doaj  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The use of theatre for development in the prevention of HIV/AIDS : a dissertation presented in partial fulfilment of the requirements for the degree Master of Philosophy in Development Studies at Massey University [PDF]

open access: yes, 2000
Over the last three decades development practitioners have begun to search for new theoretical approaches to the problems of underdevelopment. This has given rise to approaches that focus on the participation of people and their culture in development ...
Aldiss, Edmund Benet
core  

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