Results 81 to 90 of about 5,887,441 (327)

The Gut-Brain Axis: Microbial and Medicinal Effects on Mental Health and Neurodegeneration

Journal of Pure and Applied Microbiology
This comprehensive review explores the intricate connections between microbial entities and various neuropsychiatric disorders, revealing the profound impact of viruses, bacteria, and therapeutic drugs on mental health.
Mohd. Sharique Katchhi, Bhagya Venkanna Rao, Babiker Bashir Haroun Baraka, Shilpa Borehalli Mayegowda   +3 more
doaj   +1 more source

A prospective longitudinal in vivo ¹H MR spectroscopy study of the SIV/macaque model of neuroAIDS

BMC Neuroscience, 2004
Background The neurological complications of HIV infection remain poorly understood. Clinically, in vivo 1H magnetic resonance spectroscopy (MRS) demonstrates brain injury caused by HIV infection even when the MRI is normal.
Halpern Elkan, Masliah Eliezer, Sehgal Prabhat K, He Julian, Lentz Margaret R, Kim John P, Greco Jane B, Ratai Eva, Westmoreland Susan V, Fuller Robert A, Lackner Andrew A, González R Gilberto   +11 more
doaj   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

DIFFERENTIAL DIAGNOSIS OF HIV POSITIVE PATIENTS WITH NEUROLOGICAL MANIFESTATIONS

National Journal of Medical Research, 2017
Introduction: The nervous system is among the most frequent and serious target of HIV infection and is most frequently occur in patient with profound immunosuppression. 40 to 70 percent persons with HIV have neurological disorder. In 10 to 20 percent it
Ankur S Patel, HemantKumar M Shah, Ashok K Gagia, Dipika A Patel, Vinod A Dandge, Komal V Gamit, Nirmal K Patel   +6 more
doaj  

Cerebrospinal fluid HIV infection and pleocytosis: Relation to systemic infection and antiretroviral treatment

BMC Infectious Diseases, 2005
Background Central nervous system (CNS) exposure to HIV is a universal facet of systemic infection. Because of its proximity to and shared barriers with the brain, cerebrospinal fluid (CSF) provides a useful window into and model of human CNS HIV ...
Petropoulos Christos J, Liegler Teri J, Lollo Nicole D, Nilsson Annelie C, Spudich Serena S, Deeks Steven G, Paxinos Ellen E, Price Richard W   +7 more
doaj   +1 more source

Hearing loss and dementia incidence in Australia : findings from the Sydney Memory and Ageing Study

, 2019
Interventions targeting risk factors for dementia have the potential to delay or prevent a third of dementia cases. Addressing midlife hearing loss could prevent up to 9% of new cases, the highest of any potentially-modifiable risk factor identified in ...
Strutt, Paul (R21076), Savage, Gregory, Draper, Brian, Barnier, Amanda J., Brodaty, Henry, Wuthrich, Viviana   +5 more
core  

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

The pattern of central nervous system lesion in HIV-infected patients in the specialized unit of an infectious diseases hospital

Терапевтический архив, 2010
Aim. To define the incidence and features of brain lesion (BL) in HIV-infected inpatients. Subjects and methods. Four hundred and fifty-eight patients with Stage 4B HIV infection (AIDS) and central nervous system (CNS) lesion admitted to Infectious ...
Alla Borisovna Peregudova, Vasiliy Iosifovich Shakhgil'dyan, Ol'ga Olegovna Tsvetkova, Tat'yana Nikiforovna Ermak, Boris Marlenovich Gruzdev, Mikhail Vladimirovich Yuditskiy, Oleg Aleksandrovich Tishkevich, Ol'ga Yur'evna Shipulina, Mariya Viktorovna Al'vares Figeroa, Anna Petrovna Safonova, Ekaterina Alekseevna Dolgova, Dmitriy Borisovich Goncharov, A B Peregudova, V I Shakhgildyan, O O Tsvetkova, T N Yermak, B M Gruzdev, M V Yuditsky, O A Tishkevich, O Yu Shipulina, M V Alvares Figeroa, A P Safonova, E A Dolgova, D B Goncharov   +23 more
doaj  

Prediction of hearing aid cognitive outcomes in age-related hearing loss

Frontiers in Aging Neuroscience
Although the phenomena underlying cognitive decline and dementia are complex, there is growing evidence suggesting that degraded sensory inputs caused by age-related hearing loss may play a central role in accelerating cognitive decline in older ...
Patrice Voss, Zaida Escila Martinez-Moreno, Francois Prévost, Anthony Zeitouni, Alejandro Lopez Valdes, Alejandro Lopez Valdes, Alejandro Lopez Valdes, Alejandro Lopez Valdes, Etienne de Villers-Sidani   +8 more
doaj   +1 more source

AIDS Medicine and Miracles : v.6:no.1(1996)

, 1996
This issue of AIDS Medicine & Miracles features Phil Wilson, a Board Member of the non-profit, and discusses his contributions to the HIV/AIDS community as a black, gay man.

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