Results 101 to 110 of about 122,919 (308)

Highlights from the HIV Cure and Reservoir Symposium, 11-12 September 2017, Ghent, Belgium [PDF]

, 2018
For the second time, the HIV Cure Research Center (HCRC) at Ghent University organised the HIV Cure and Reservoir Symposium, in Ghent, Belgium, where in this two-day conference, virologists, molecular biologists, immunologists and clinicians presented ...
Cole, Basiel, Kint, Sam, Sips, Magdalena, Van Hecke, Clarissa, Vandekerckhove, Linos   +4 more
core   +1 more source

Viral Infection‐Inspired Autonomous Detection of Fusion‐Competent Viruses for Screening and Environmental Surveillance

Advanced Materials, EarlyView.
Inspired by viral entry mechanisms, the FUSION assay enables autonomous detection of respiratory viruses via membrane fusion–triggered CRISPR‐Cas13a activation. VEACON selectively fuses with fusion‐competent viruses, triggering fluorescence within confined vesicles.
Jae Chul Park, Yidam Song, Hyun‐Woo Choi, Jaeuk Sung, Harin Jin, WonSeok Gwak, Kirim Yoo, Soohwang Lee, Jongeon Park, Jeongmin Kim, Hye‐Jun Jo, Jahyun Koo, Youngdo Jeong, Kwan Hyi Lee, Seung‐Jung Kee, Hojun Kim   +15 more
wiley   +1 more source

Increase in H5N1 vaccine antibodies confers cross-neutralization of highly pathogenic avian influenza H5N1

Nature Communications
H5N1, a highly pathogenic avian influenza virus, presents pandemic risks due to its ability to adapt and spread among mammalian species. Vaccination may control its spread, but the effectiveness of existing H5N1 vaccines against circulating strains ...
Xiande Huang, Dan Yu, Ling Pan, Xi Wu, Jun Li, Dayan Wang, Liqi Liu, Chenyan Zhao, Weijin Huang   +8 more
doaj   +1 more source

IgG3 collaborates with IgG1 and IgA to recruit effector function in RV144 vaccinees

JCI Insight, 2020
While the RV144 HIV vaccine trial led to moderately reduced risk of HIV acquisition, emerging data from the HVTN702 trial point to the critical need to reexamine RV144-based correlates of reduced risk of protection.
Stephanie Fischinger, Sepideh Dolatshahi, Madeleine F. Jennewein, Supachai Rerks-Ngarm, Punnee Pitisuttithum, Sorachai Nitayaphan, Nelson Michael, Sandhya Vasan, Margaret E. Ackerman, Hendrik Streeck, Galit Alter   +10 more
doaj   +1 more source

Boosting the Immunization Workforce: Lessons from the Merck Vaccine Network - Africa [PDF]

, 2012
This report shares lessons learned from The Merck Company Foundation's decade of experience building immunization capacity in Africa. The Merck Vaccine Network -- Africa, a philanthropic initiative to train immunization managers in Kenya, Mali, Uganda ...
Amanda Rinderle, Greg Hills, Leigh Fiske
core  

Vat Polymerization 3D Printing for Controlled Drug Release Applications

Advanced Materials Technologies, EarlyView.
ABSTRACT Vat polymerization (VP) 3D printing, a light‐based additive manufacturing technique, has emerged as a promising technique for fabricating complex drug delivery systems with high precision and spatial resolution. This layer‐by‐layer manufacturing process enables the creation of intricate geometries and customizable architectures, which are ...
Hafiz Busari, O. Thompson Mefford, M. Aaron Vaughn   +2 more
wiley   +1 more source

Preservation of Extracellular Vesicle Integrity and Cargo Using Spiral Microfluidic Chip‐Based Separation

Advanced Materials Technologies, EarlyView.
A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee, Sehyeon Kim, Dasom Kong, Hye‐min Park, Hyun‐Ji Park, Jinsik Kim   +5 more
wiley   +1 more source

AIDS Vaccines [PDF]

Nature Biotechnology, 1993
Sean Henahan, Gill Higgins
openaire   +2 more sources

Dual‐Functional Ingestible Passive Capsules for High‐Throughput Intestinal Sampling with Sealed Containment and Targeted Drug Delivery

Advanced Robotics Research, EarlyView.
To address challenges in high‐throughput intestinal sampling with sealed containment and target drug delivery, we developed a dual‐functional ingestible passive capsule with a dual‐triggered control system based on pH‐response and mechanical actuation.
Libing Huang, Houyu Ling, Xizong Chen, Yufei Duan, Yu Liu, Shuntian Cai, Yandan Ren, Wenlong Li, Lei Ren, Miao Wang   +9 more
wiley   +1 more source

Advantages of Broad-Spectrum Influenza mRNA Vaccines and Their Impact on Pulmonary Influenza

Vaccines
Influenza poses a significant global health challenge due to its rapid mutation and antigenic variability, which often leads to seasonal epidemics and frequent outbreaks.
Ziqi Cheng, Junfeng Ma, Chenyan Zhao
doaj   +1 more source