Results 71 to 80 of about 6,351,769 (402)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Assessment of Factors Contributing to Refrigerator Cycling Losses [PDF]

open access: yes, 1993
Thermal mass effects, refrigerant dynamics, and interchanger transients are three factors affecting the transient and cycling performance of all refrigeration and air conditioning equipment.
Bullard, C.W., Rubas, P.J.
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Investigation of an R134A Refrigerant/Iso 32 Polyol Ester Oil Mixture in Condensation [PDF]

open access: yes, 2001
Air Conditioning and Refrigeration Project ...
Chato, J.C.   +2 more
core  

Experimental and theoretical research on the electrical conductivity of a liquid desiccant for the liquid desiccant air-conditioning system: LiCl aqueous solution [PDF]

open access: yes, 2018
At present, the energy consumption in buildings occupies a large proportion of total energy use, and air-conditionings cost a large proportion of energy in the buildings. The liquid desiccant air-conditioning system has a good energy saving potential and
Cheng, Q, Feng, W, Wang, H, Xu, W
core   +1 more source

Air Conditioning Energy Saving from Cloud-Based Artificial Intelligence: Case Study of a Split-Type Air Conditioner

open access: yesEnergies, 2020
This study developed cloud-based artificial intelligence (AI) that could run AI programs in the cloud and control air conditioners remotely from home. AI programs in the cloud can be altered any time to provide good control performances without altering ...
Dasheng Lee, Fu-Po Tsai
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

UK domestic air conditioning: a study of occupant use and energy efficiency [PDF]

open access: yes, 2008
This paper presents the results of a study of air-conditioning usage in homes in the southeast of England. First part of the study consisted surveying 13 dwellings with air-conditioning for a series of 4 week periods during the summer of 2004.
Oreszczyn, T., Pathan, A., Young, A.
core  

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

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