Results 71 to 80 of about 743,793 (309)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Local magnetic measurements in magnetic circuits with highly nonuniform electromagnetic fields [PDF]
, 2009 In this paper, local magnetic measurements are carried out in magnetic circuits with highly non uniform electromagnetic field patterns, including excitation winding and/or air gaps, as in the case of rotating electrical machines.
Dupré, Luc +1 more
core
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Air Force Operational Contracting Knowledge Assessment: analyzing explicit and tacit contracting knowledge [PDF]
, 2011 MBA Professional ReportThe Defense Acquisition Workforce Improvement Act (DAWIA) establishes education and training standards for acquisition personnel. These standards culminate into ascending levels of certification for acquisition professionals based ...
Aufderheide, Derek +2 more
core +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
The Journal of Engineering, 2020 This study analyses a double Y shaft 30° winding for six-phase fault-tolerant permanent magnet synchronous motors and introduces a novel modular 18-slot stator topology used in high-performance electric vehicles with unequal teeth width and unequal slot ...
Zhong An Yu +3 more
doaj +1 more source
External walls partially filled with insulation, and the potential to "top-up" the residual cavity. [PDF]
, 2015 This review found that the connecting voids in partially filled cavity walls leads to considerable variation in thermal performance. Whilst photographic records found considerable evidence of gaps in the insulation resulting from poor site practice and ...
Gorse, C, Miles-Shenton, D, Thomas, F
core
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Robust topology optimization of three-dimensional photonic-crystal band-gap structures [PDF]
, 2014 We perform full 3D topology optimization (in which "every voxel" of the unit cell is a degree of freedom) of photonic-crystal structures in order to find optimal omnidirectional band gaps for various symmetry groups, including fcc (including diamond ...
Freund, Robert M. +4 more
core +2 more sources