Results 51 to 60 of about 5,648,704 (342)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The Journal of Engineering, 2019 The frequent forest fires become a serious threat to the performance of transmission lines’ external insulation, therefore, researches on the breakdown characteristics under flame conditions is of great significance for the transmission lines ...
Daochun Huang, Wei Lu, Tao Yao, Peng Li
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Local magnetic measurements in magnetic circuits with highly nonuniform electromagnetic fields [PDF]
, 2009 In this paper, local magnetic measurements are carried out in magnetic circuits with highly non uniform electromagnetic field patterns, including excitation winding and/or air gaps, as in the case of rotating electrical machines.
Dupré, Luc +1 more
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Banded transformer cores [PDF]
, 1974 A banded transformer core formed by positioning a pair of mated, similar core halves on a supporting pedestal. The core halves are encircled with a strap, selectively applying tension whereby a compressive force is applied to the core edge for reducing ...
Mclyman, C. W. T.
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Applied SciencesThis study primarily simulates the flashover phenomenon between the metal fittings (rods) and the skirt surface (plates) of insulators when water droplets traverse between them under heavy rain conditions.
Jianli Zhao +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Use of fractional-conductor windings and semi-magnetic slot wedges in synchronous machines
The Journal of Engineering, 2019 This paper discusses two methods of altering the harmonic content of the spatial air-gap flux density waveform in synchronous machines (generators and motors).
Christopher Donaghy-Spargo +2 more
doaj +1 more source