Results 71 to 80 of about 5,648,704 (342)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

The Wide‐Band Multisection Wilkinson Power Divider Based on RGW for X‐ and Ku‐Band Applications

open access: yesIET Microwaves, Antennas & Propagation
This paper presents the design, simulation and fabrication of a wideband Wilkinson power divider (WPD) based on ridge gap waveguide (RGW) technology for operation in the X‐ and Ku‐band frequency range (8–18 GHz).
Reza Afroozeh   +2 more
doaj   +1 more source

Electrical field distribution of 35 KV Igla under polluted and ice-covered situation at power frequency

open access: yesThe Journal of Engineering, 2019
Lightning striking on power system may lead to severe accident and huge losses, which is the reason why line arresters are needed. During operation, the electrical field concentration in line arrester may lead to ablation and accelerated aging of ...
Guo Jie   +4 more
doaj   +1 more source

A machine learning‐based approach for dielectric strength prediction of long air gaps with engineering configurations

open access: yesIET Generation, Transmission & Distribution, 2022
It is a long‐term goal in external insulation studies to determine the discharge voltages of complicated engineering gaps by simulation methods.
Zhibin Qiu   +4 more
doaj   +1 more source

Topological transitions in continuously-deformed photonic crystals

open access: yes, 2018
We demonstrate that multiple topological transitions can occur, with high-sensitivity, by continuous change of the geometry of a simple 2D dielectric-frame photonic crystal consisting of circular air-holes.
Jiang, Jian-Hua   +5 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Impact of Self-Contained Breathing Apparatus on Air Gaps in Structural Firefighting Personal Protective Clothing

open access: yesApplied Sciences
The self-contained breathing apparatus (SCBA) is an integral part of the structural firefighting personal protective equipment (PPE) ensemble. However, when donned, it adds significant weight and restriction, interfering with the fit of the turnout suit ...
Josephine Bolaji, Meredith McQuerry
doaj   +1 more source

Accuracy improvement for complex harmonic analysis modelling of a wound field synchronous generator

open access: yesThe Journal of Engineering, 2019
Complex harmonic analysis (CHA) provides a computationally efficient alternative to finite element analysis (FEA) for modelling multi-phase wound field synchronous machines. This paper presents three methods that could improve the accuracy of the CHA: by
Xiaotao Zhang   +2 more
doaj   +1 more source

Equivalent Permeability of Step-Lap Joints of Transformer Cores: Computational and Experimental Considerations [PDF]

open access: yes, 2011
The paper develops an efficient computational method for establishing equivalent characteristics of magnetic joints of transformer cores, with special emphasis on step-lap design.
Hihat, N.   +4 more
core   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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