Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
ADS-B data gating technique and its probabilistic models
Научный вестник МГТУ ГА, 2023 The article developed a gating technique that allows us to validate ADS-B data without the necessity to verify using the secondary surveillance radar or multilateration.
E. A. Rubtsov +3 more
doaj +1 more source
Accumulation-mode aerosol number concentrations in the Arctic during the ARCTAS aircraft campaign: Long-range transport of polluted and clean air from the Asian continent [PDF]
, 2011 We evaluate the impact of transport from midlatitudes on aerosol number concentrations in the accumulation mode (light-scattering particles (LSP) with diameters >180 nm) in the Arctic during the Arctic Research of the Composition of the Troposphere ...
Anderson, BE +14 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Research on Mobile Network Parameters Using Unmanned Aerial Vehicles
SensorsThe study of phenomena related to the propagation of electromagnetic waves is a necessity with the development of mobile telephony networks. This paper deals with the problem of the quality of mobile telephony signals.
Jan Warczek +4 more
doaj +1 more source
Transport, 2010 Regional aircraft are playing a significant role in airline operations. This paper considers the problem of selecting an appropriate aircraft from the airline fleet for optimal regional air travel realization. Complexity balance between air travel demand
Olja Čokorilo +3 more
doaj +1 more source
Properties of air and combustion products of fuel with air [PDF]
, 1975 Thermodynamic and transport properties have been calculated for air, the combustion products of natural gas and air, and combustion products of ASTM-A-1 jet fuel and air. Properties calculated include: ratio of specific heats, molecular weight, viscosity,
Poferl, D. J., Svehla, R. A.
core +1 more source
Virtual Integration Platforms (VIP) –A Concept for Integrated and Interdisciplinary Air Transportation Research and Assessment [PDF]
, 2011 The paper descibes a new methodology for a holistic development of air transportation concepts. The Virtual Integration Plattform (VIP) concept is based on an IT tool chain as well as human collaborative methods to deal with complex systems.
Gollnick, Volker +3 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The Occurrence of Heavy Air Pollution during the COVID-19 Outbreak in Beijing, China: Roles of Emission Reduction, Meteorological Conditions, and Regional Transport [PDF]
, 2021 Xiao Yan +11 more
openalex +1 more source