Results 21 to 30 of about 146,689 (316)

Clinical and immunological characteristics of diabetes mellitus in patients with autoimmune polyglandular syndrome type 1 in Russia

Сахарный диабет, 2018
Background. Autoimmune polyglandular syndrome type 1 (APS type 1) is a rare inherited autoimmune disease caused by mutations in AIRE gene (autoimmune regulator) and characterized by list of components.
Leila S. Sozaeva, Lubov I. Zilberman, Galina N. Svetlova, Ekaterina A. Andrianova, Maria A. Kareva, Olga N. Ivanova, Svetlana M. Stepanova, Larisa V. Savelyeva, Alexandr Y. Mayorov, Ekaterina A. Troshina, Elizaveta M. Orlova, Eystein S. Husebye, Valentina A. Peterkova   +12 more
doaj   +1 more source

La Aviación Militar Española: una historia corta pero de gran intensidad

Arbor: Ciencia, Pensamiento y Cultura, 2002
En este artículo, su autor hace un recorrido histórico, excelentemente documentado, por toda la historia de la Aviación Militar Española, desde sus inicios, allá por 1910, hasta nuestros días.
José Sánchez Méndez
doaj   +1 more source

Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia. [PDF]

, 2014
Promiscuous gene expression (PGE) by thymic epithelial cells (TEC) is essential for generating a diverse T cell antigen receptor repertoire tolerant to self-antigens, and thus for avoiding autoimmunity. Nevertheless, the extent and nature of this unusual
Nusspaumer, G, Holländer, GA, Shikama-Dorn, Noriko, Ponting, Chris P., Nusspaumer, Gretel, Heger, A, Deadman, Mary E., Sansom, SN, Deadman, ME, Shikama-Dorn, N, Holländer, Georg A., Heger, Andreas, Macaulay, IC, Sansom, Stephen N., Zhanybekova, S, Zhanybekova, Saule, Sansom, Stephen, Macaulay, Iain C., Ponting, CP   +18 more
core   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

Arthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler, Joshua F. Baker, Jennifer L. Barton, Maria I. Danila, Tate M. Johnson, Kamini Kuchinad, Kaleb Michaud, Amir A. Razmjou, J. Steuart Richards, Namrata Singh, Isaac D. Smith, Katherine D. Wysham, Grant W. Cannon, Bryant R. England, Amy Joseph, Deana Lazaro, Katherine P. Liao, Courtney Loecker, Andreas Reimold, Beth I. Wallace, Ted R. Mikuls   +20 more
wiley   +1 more source

A case-crossover analysis to quantify the impact of wildfire smoke on hospital respiratory admissions in the Rogue Valley, Oregon

Public Health in Practice
Background: With the increasing prevalence of wildfire smoke in the Pacific Northwest, it is important to quantify health impacts to plan for adequate health services.
A Lee Mitchell, Kyle Chapman, Kerry Farris, Pooya Naderi, Ashley Hansen   +4 more
doaj   +1 more source

Diseño y construcción de colectores de admisión de aire con tomas individuales para cada cilindro del motor de un vehículo Chevrolet corsa evolution

Innova Research Journal, 2016
El presente articulo responde al deseo de crear una modificación en el sistema de admisión de aire en un motor de combustión interna con inyección electrónica de combustible, mediante el diseño y construcción de un múltiple para el vehículo Chevrolet ...
Juan José Castro Mediavilla
doaj   +1 more source

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Ensayos de control del concreto lanzado con fibras en el túnel de la línea 12 del metro de la CDMX

Revista ALCONPAT, 2021
En este artículo se evalúan tres ensayos para caracterizar el comportamiento del concreto lanzado con fibras metálicas en el revestimiento primario del túnel de la línea 12 del metro de la CDMX.
Carlos Aire, Lilia Aguilar
doaj   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

El movimiento de proyectiles en la mecánica de Diego Hurtado de Mendoza y la nueva dinámica renacentista

Asclepio: Revista de Historia de la Medicina y de la Ciencia, 2011
Este artículo examina la traducción hecha por Diego Hurtado de Mendoza de la Mecánica aristotélica en el contexto del ambiente científico-humanista italiano de mediados del siglo XVI.
Virginia Iommi Echeverría
doaj   +1 more source