Results 41 to 50 of about 110,250 (294)

TRPV4-A Missing Link Between Mechanosensation and Immunity [PDF]

open access: yes, 2020
Transient receptor potential vanilloid-type 4 (TRPV4) cation channel is widely expressed in all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel seems to be conserved throughout all mammalian species. Of late, emerging
Kuebler, Wolfgang M., Michalick, Laura
core   +1 more source

Airway Mucus Hypersecretion in Chronic Obstructive Pulmonary Disease Patients: From Basic Pathophysiology to Rehabilitation Approaches

open access: yesSurabaya Physical Medicine and Rehabilitation Journal
Objective: This narrative review aimed to describe the pathophysiology of mucus accumulation and mucus expectoration disorders, rehabilitation assessments, and airway clearance techniques in chronic obstructive pulmonary disease (COPD) patients ...
Arnengsih Nazir, Brandon Clementius
doaj   +1 more source

Management of Bronchiectasis in Adults

open access: yesBarcelona Respiratory Network Reviews, 2022
Bronchiectasis is a highly heterogeneous disease in its clinical presentation, severity and treatment response, making the therapeutic approach challenging.
Mariana Conceição, James D. Chalmers
doaj   +1 more source

Nanoparticles in the treatment of chronic lung diseases [PDF]

open access: yes, 2019
Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G   +9 more
core   +2 more sources

Liquid fluorocarbon lavage to clear thrombus from the distal airways after severe pulmonary hemorrhage requiring extracorporeal life support (ECLS)

open access: yesRespiratory Medicine Case Reports, 2015
Massive pulmonary hemorrhage can pose a significant therapeutic challenge. Traditional methods of airway clearance using saline lavage and direct thrombus removal via bronchoscopy have limited ability to retrieve thrombi from deep airways.
Christopher M. Horvat   +2 more
doaj   +1 more source

Consequences of cystic fibrosis transmembrane regulator mutations on inflammatory cells [PDF]

open access: yes, 2016
Recent studies in cystic fibrosis (CF) transmembrane regulator (CFTR) mutations and function have shed light on its involvement in disease progression. The extent of cell and tissue distribution of CFTR facilitates systemic dysfunction of ion transport ...
Castro, Guillermo Raul   +2 more
core   +1 more source

Environmental pollutants damage airway epithelial cell cilia: Implications for the prevention of obstructive lung diseases

open access: yesThoracic Cancer, 2020
Mucociliary epithelium lining the upper and lower respiratory tract constitutes the first line of defense of the airway and lungs against inhaled pollutants and pathogens.
Yu Cao   +4 more
doaj   +1 more source

Multinational Validation of \u3cem\u3eAnxiety\u3c/em\u3e, \u3cem\u3eHopelessness\u3c/em\u3e, and \u3cem\u3eIneffective Airway Clearance\u3c/em\u3e [PDF]

open access: yes, 1991
The effective use of nursing diagnosis internationally depends in part on incorporating language and cultural difference into the common language of nursing. International validation studies can provide a basis for this effort.
Fadden, Teresa   +2 more
core   +1 more source

Targeted therapies to improve CFTR function in cystic fibrosis [PDF]

open access: yes, 2015
Cystic fibrosis is the most common genetically determined, life-limiting disorder in populations of European ancestry. The genetic basis of cystic fibrosis is well established to be mutations in the cystic fibrosis transmembrane conductance regulator ...
Brodlie, M   +3 more
core   +2 more sources

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

open access: yesFEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng   +2 more
wiley   +1 more source

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