Results 41 to 50 of about 110,250 (294)
TRPV4-A Missing Link Between Mechanosensation and Immunity [PDF]
Transient receptor potential vanilloid-type 4 (TRPV4) cation channel is widely expressed in all tissues as well as in immune cells and its function as mechanosensitive Ca2+ channel seems to be conserved throughout all mammalian species. Of late, emerging
Kuebler, Wolfgang M., Michalick, Laura
core +1 more source
Objective: This narrative review aimed to describe the pathophysiology of mucus accumulation and mucus expectoration disorders, rehabilitation assessments, and airway clearance techniques in chronic obstructive pulmonary disease (COPD) patients ...
Arnengsih Nazir, Brandon Clementius
doaj +1 more source
Management of Bronchiectasis in Adults
Bronchiectasis is a highly heterogeneous disease in its clinical presentation, severity and treatment response, making the therapeutic approach challenging.
Mariana Conceição, James D. Chalmers
doaj +1 more source
Nanoparticles in the treatment of chronic lung diseases [PDF]
Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G +9 more
core +2 more sources
Massive pulmonary hemorrhage can pose a significant therapeutic challenge. Traditional methods of airway clearance using saline lavage and direct thrombus removal via bronchoscopy have limited ability to retrieve thrombi from deep airways.
Christopher M. Horvat +2 more
doaj +1 more source
Consequences of cystic fibrosis transmembrane regulator mutations on inflammatory cells [PDF]
Recent studies in cystic fibrosis (CF) transmembrane regulator (CFTR) mutations and function have shed light on its involvement in disease progression. The extent of cell and tissue distribution of CFTR facilitates systemic dysfunction of ion transport ...
Castro, Guillermo Raul +2 more
core +1 more source
Mucociliary epithelium lining the upper and lower respiratory tract constitutes the first line of defense of the airway and lungs against inhaled pollutants and pathogens.
Yu Cao +4 more
doaj +1 more source
Multinational Validation of \u3cem\u3eAnxiety\u3c/em\u3e, \u3cem\u3eHopelessness\u3c/em\u3e, and \u3cem\u3eIneffective Airway Clearance\u3c/em\u3e [PDF]
The effective use of nursing diagnosis internationally depends in part on incorporating language and cultural difference into the common language of nursing. International validation studies can provide a basis for this effort.
Fadden, Teresa +2 more
core +1 more source
Targeted therapies to improve CFTR function in cystic fibrosis [PDF]
Cystic fibrosis is the most common genetically determined, life-limiting disorder in populations of European ancestry. The genetic basis of cystic fibrosis is well established to be mutations in the cystic fibrosis transmembrane conductance regulator ...
Brodlie, M +3 more
core +2 more sources
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source

