Results 211 to 220 of about 162,572 (266)
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Aging Clinical and Experimental Research, 2013
Since little is known of airways inflammation in the elderly, we have carried out a study to explore the presence of some inflammatory markers in the airways of healthy subjects of different ages using a non-invasive method which is particularly suitable for aged people.The aim of this work was to investigate whether parameters, including (1) pH, IL-8 ...
Carpagnano, G. E. +4 more
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Since little is known of airways inflammation in the elderly, we have carried out a study to explore the presence of some inflammatory markers in the airways of healthy subjects of different ages using a non-invasive method which is particularly suitable for aged people.The aim of this work was to investigate whether parameters, including (1) pH, IL-8 ...
Carpagnano, G. E. +4 more
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The Concept of Airway Inflammation
American Journal of Respiratory and Critical Care Medicine, 2000The generation of an inflammatory response is a critical mechanism through which mammalian species respond to and protect themselves from infectious as well as noninfectious insults (1). In terms of the lung, both nonspecific and antigen-specific (immune) mechanisms may lead to an inflammatory response.
G L, Larsen, P G, Holt
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Airway Inflammation in Childhood Asthma
American Journal of Respiratory and Critical Care Medicine, 2003Abstract Airway pathology has been extensively investigated in adulthood asthma, whereas only few studies examined bronchial biopsies in childhood asthma. To evaluate the airway pathology in children with asthma, we analyzed bronchial biopsies obtained from 23 children undergoing bronchoscopy for clinical indications other than asthma.
BARBATO, ANGELO +10 more
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Neurogenic Inflammation in Airways
International Archives of Allergy and Applied Immunology, 2009Neurogenic inflammation, due to release of neuropeptides from sensory nerves, has been demonstrated in airways of several species, particularly rodents, and may contribute to the inflammatory response in asthmatic airways. Tachykinins (substance P and neurokinin A) and calcitonin-gene-related peptide released from airway sensory nerves may cause ...
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Neurogenic inflammation in the airways
Respiration Physiology, 2001Release of neuropeptides, including tachykinins and calcitonin gene-related peptide, from sensory nerves via an axon or local reflex may have inflammatory effects in the airways. This neurogenic inflammation may be initiated by activation of sensory nerves by inflammatory mediators and irritants. Neurogenic inflammation is well developed in rodents and
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Purinergic Regulation of Airway Inflammation
2011The immune and inflammatory responses initiated by the interaction of a pathogen with airway surfaces constitute vital mechanisms to eradicate an infection. Sentinel dendritic cells embedded in the mucosa migrate to the lymph nodes to induce immune responses, whereas epithelial cells release chemokines to recruit inflammatory cells engaged in the ...
M. KOEPPEN +3 more
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Airway fibrosis in a mouse model of airway inflammation
Toxicology and Applied Pharmacology, 2003BALB/c mice were sensitized to ovalbumin by systemic injection and then exposed for up to 8 weeks to ovalbumin aerosols in whole body chambers. A pattern of airway inflammation, mucous cell hypertrophy and hyperplasia, and airway remodeling with submucosal fibrosis was observed as lesions evolved over time.
Nicholas J, Kenyon +2 more
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The Effects of Theophylline on Airway Inflammation
Chest, 1987One of the important modes of action of theophylline in asthma and chronic obstructive airway disease may be the inhibition of airway inflammation. This hypothesis is based on in vitro and in vivo studies demonstrating that theophylline at therapeutic concentrations has an inhibitory activity on airway inflammation induced by allergic and nonallergic ...
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Posttranscriptional control of airway inflammation
WIREs RNA, 2017Acute inflammation in the lungs is a vital protective response, efficiently and swiftly eliminating inciters of tissue injury. However, in respiratory diseases characterized by chronic inflammation, such as chronic obstructive pulmonary disease and asthma, enhanced expression of inflammatory mediators leads to tissue damage and impaired lung function ...
Wendy, Ezegbunam, Robert, Foronjy
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Adiposity, asthma, and airway inflammation
Journal of Allergy and Clinical Immunology, 2007Several studies have found obesity to be associated with an increased prevalence of asthma. For reasons that remain unclear, this association has often been reported to be stronger in women than in men. One possible explanation might be that these studies have used body mass index to identify adiposity, which might be a less reliable measure of body ...
Christene R, McLachlan +10 more
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