Results 191 to 200 of about 959,395 (302)

Loss of POGLUT2/3‐mediated O‐glucosylation produces lung and aortic phenotypes reminiscent of fibrillin1 mutants

Developmental Dynamics, EarlyView.
Abstract Background Fibrillins provide a scaffold for elastic fiber formation, which enables lung recoil and aortic compliance. Abnormal fibrillin microfibrils, as in Marfan syndrome, lead to enlarged alveoli, vascular stiffening, and aneurysms. Our earlier studies suggested that fibrillin function depends on O‐glucosylation of its epidermal growth ...
Sanjiv Neupane, Angelina Almiroudis, Kaitlyn E. Donnelly, Robert S. Haltiwanger, Bernadette C. Holdener   +4 more
wiley   +1 more source

<i>Ex vivo</i> modeling of nasal epithelial airway inflammation in respiratory viral infections. [PDF]

Front Microbiol
Fotoohabadi L, Kombe Kombe AJ, Tamang PL, Klawinsky S, Mitakidis M, Ablyazova K, Pyles R, Kelesidis T.   +7 more
europepmc   +1 more source

Alleviation of Chitin- and Ovalbumin-Induced Steroid-Resistant Eosinophilic Airway Inflammation Associated with NLRP3 Axis Inhibition in a Mouse Model. [PDF]

J Inflamm Res
Matsuda SU, Harada N, Harada S, Sasano H, Nishimaki T, Sato Y, Abe S, Sandhu Y, Tanabe Y, Takeshige T, Chiba A, Akiba H, Miyake S, Takahashi K.   +13 more
europepmc   +1 more source

Biomarkers of lung congestion and injury in acute heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi, Gabriele Novello, Francesca Bursi, Anna Caretti, Noemi Furlotti, Ross Arena, Paola Argiento, Julio Núñez, Antoni Bayes‐Genis, Marco Metra   +9 more
wiley   +1 more source

SREBP2 promotes macrophage alternative activation and allergic airway inflammation independent of cholesterol biosynthesis. [PDF]

Cell Death Dis
Wu Y, Zheng K, Dong L, Gao S, Wu Y, Liu Z, Li J, Chen H, Weng Q, Li M, Zhu C, Xu J, Ying S, Chen Z, Li W.   +14 more
europepmc   +1 more source

Exploring the efficacy and safety of perampanel in epilepsia partialis continua: A case series

Epileptic Disorders, EarlyView.
Abstract Background Epilepsia partialis continua (EPC) is a form of focal motor status epilepticus (SE), which is commonly drug‐resistant requiring treatment with multiple antiseizure medications (ASM). There are no established guidelines for pharmacological management.
Setareh Lahsaee, Kristin M. Ikeda, Stephanie Woodroffe, Benjamin P. Whatley   +3 more
wiley   +1 more source

Synergistic interactions of melatonin and glucocorticoids in alleviating allergic airway inflammation. [PDF]

Front Med (Lausanne)
Zhang Z, Wang J, Ma T, Zhang X, Chen G, Wang B.   +5 more
europepmc   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Chimeric allergen receptor regulatory T cells suppress birch pollen allergic airway inflammation. [PDF]

J Exp Med
Alcaraz-Serna A, Chillier N, Trompette A, Ermellino L, Porret R, Lana E, Cecchin R, Shanmuganathan A, Guney S, Alfageme-Abello O, Pace E, Mancarella A, Campos J, Foglierini M, von Garnier C, Fenwick C, Perez L, Ubags N, Muller YD.   +18 more
europepmc   +1 more source

Incidence and impact of respiratory tract infections on outcomes in patients with status epilepticus: A 20‐year longitudinal observation

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to identify the incidence of respiratory tract infections (RTIs) in a large cohort of adult patients with status epilepticus (SE) and to characterize their associations with clinical features and outcome determinants.
Sebastian Berger, Sira M. Baumann, Urs Fisch, Lisa Hert, Pascale Grzonka, Sabina Hunziker, Stephan Rüegg, Sarah Tschudin‐Sutter, Raoul Sutter   +8 more
wiley   +1 more source