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Airway Remodeling in Asthma [PDF]

Frontiers in Medicine, 2020
Asthma is an inflammatory disease of the airways that may result from exposure to allergens or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of breath.
Kenneth P Hough, Rui-Ming Liu, Jennifer Trevor   +2 more
exaly   +5 more sources

Airway Remodeling in Asthma

Allergology International, 2007
Airway remodeling can be defined as changes in the composition, content, and organization of the cellular and molecular constituents of the airway wall.
Qutayba Hamid
exaly   +5 more sources

Airway remodeling in chronic obstructive pulmonary disease: characteristics and opportunities [PDF]

Frontiers in Medicine
Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease characterized by irreversible airway remodeling and is a global burden on the healthcare system.
Minjie Pan, Xiaojing Zhou
doaj   +2 more sources

IFITM1 is required for epithelial mesenchymal transition in airway remodeling of allergic asthma [PDF]

World Allergy Organization Journal
Background: Interferon-induced transmembrane protein 1 (IFITM1) restricts virus infection. IFITM proteins are involved in Th2 cell differentiation in allergic asthma. The epithelial‒mesenchymal transition (EMT) regulates allergic airway remodeling.
Manni Zhu, MD, Xiaoqin Weng, MD, Chuanli Zhang, MD, Xiaofei Song, MD, Shan Liu, MD, Tingting Xu, MD, Zhengxia Wang, MD, Zhongqi Chen, MD, Mingshun Zhang, MD, Mao Huang, MD, Ningfei Ji, MD   +10 more
doaj   +2 more sources

Airway Remodeling and Airway Smooth Muscle in Asthma

Allergology International, 2006
Airway remodeling in asthma has been recognized as structural changes of airways such as smooth muscle hypertrophy (an increase in size of airway smooth muscle cells) and hyperplasia (an increase in the number of airway smooth muscle cells), thickening ...
Mitsuru Munakata
doaj   +3 more sources

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα [PDF]

Advanced Science
Asthma is a prevalent chronic airway disorder characterized by airway hyperresponsiveness (AHR), persistent airway inflammation, and airway remodeling.
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
doaj   +2 more sources

Drugs Used in the Treatment of Viral Infections for the Prevention of Airway Remodeling in Asthma [PDF]

Mediators of Inflammation
One of the main causes of the exacerbation of chronic airway inflammatory diseases is respiratory virus infections. The most prevalent viruses that can infect humans multiple times a year are rhinovirus (RV) and respiratory syncytial virus (RSV). Because
Joanna Wieczfinska, Rafal Pawliczak
doaj   +2 more sources

Mechanisms of Airway Remodeling in Asthma

Allergology International, 2007
Asthma is a chronic inflammatory disease characterized by reversible airflow limitation and airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to structural changes known as airway remodeling and consequently airway ...
Etsuko Tagaya, Jun Tamaoki
doaj   +3 more sources

How does cigarette smoking affect airway remodeling in asthmatics?

Tobacco Induced Diseases, 2023
Asthma is a prevalent chronic airway inflammatory disease involving multiple cells, and the prolonged course of the disease can cause airway remodeling, resulting in irreversible or partial irreversible airflow limitation and persistent airway ...
Huihui Lin, Hequan Li
doaj   +1 more source

Airway Remodeling in Asthma. [PDF]

Open Respir Arch
Tiotiu A.
europepmc   +4 more sources