Results 11 to 20 of about 45,718 (290)
Canadian Respiratory Journal, 2023 Objective. Dysregulation of epithelial-mesenchymal transition (EMT) in the airway epithelium is associated with airway remodeling and the progression of pulmonary fibrosis.
Hongjuan He +6 more
doaj +2 more sources
Central role of cellular senescence in TSLP-induced airway remodeling in asthma. [PDF]
PLoS ONE, 2013 BACKGROUND:Airway remodeling is a repair process that occurs after injury resulting in increased airway hyper-responsiveness in asthma. Thymic stromal lymphopoietin (TSLP), a vital cytokine, plays a critical role in orchestrating, perpetuating and ...
Jinxiang Wu +8 more
doaj +2 more sources
Novel Lung Growth Strategy with Biological Therapy Targeting Airway Remodeling in Childhood Bronchial Asthma [PDF]
Children, 2022 Anti-inflammatory therapy, centered on inhaled steroids, suppresses airway inflammation in asthma, reduces asthma mortality and hospitalization rates, and achieves clinical remission in many pediatric patients.
Mitsuru Tsuge +2 more
doaj +3 more sources
Rhinovirus induces airway remodeling: what are the physiological consequences?
Respiratory Research, 2023 Background Rhinovirus infections commonly evoke asthma exacerbations in children and adults. Recurrent asthma exacerbations are associated with injury-repair responses in the airways that collectively contribute to airway remodeling.
Cassandra Spector +3 more
doaj +2 more sources
Research trends on airway remodeling: A bibliometrics analysis
HeliyonBackground: Airway remodeling is an essential pathological basis of respiratory diseases such as asthma and COPD, which is significantly related to pulmonary function and clinical symptoms.
Pengcheng Liu +7 more
doaj +2 more sources
Airway Remodeling in Feline Lungs [PDF]
Topics in Companion Animal Medicine, 2022 Airway remodeling encompass structural changes that occur as the result of chronic injury and lead to persistently altered airway structure and function. Although this process is known in several human respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD), airway remodeling is poorly characterized in the feline ...
D'Annunzio G. +5 more
openaire +4 more sources
Increased expression of cathepsin C in airway epithelia exacerbates airway remodeling in asthma
JCI InsightAirway remodeling is a critical factor determining the pathogenesis and treatment sensitivity of severe asthma (SA) or uncontrolled asthma (UA). The activation of epithelial-mesenchymal trophic units (EMTUs) regulated by airway epithelial cells (AECs ...
Lin Yuan +16 more
doaj +2 more sources
Impact of obesity on airway remodeling in asthma: pathophysiological insights and clinical implications [PDF]
Frontiers in AllergyThe prevalence of obesity among asthma patients has surged in recent years, posing a significant risk factor for uncontrolled asthma. Beyond its impact on asthma severity and patients' quality of life, obesity is associated with reduced lung function ...
Aditya Sri Listyoko +5 more
doaj +2 more sources
Role of inflammatory cells in airway remodeling in COPD [PDF]
International Journal of COPD, 2018 Yujie Wang,1,2 Jiayan Xu,1 Yaqi Meng,1 Ian M Adcock,3 Xin Yao1 1Department of Respiratory Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China; 2Department of Respiratory Medicine, The Second Affiliated Hospital of ...
Wang Y, Xu J, Meng Y, Adcock IM, Yao X
doaj +2 more sources
Airway remodeling heterogeneity in asthma and its relationship to disease outcomes
Frontiers in Physiology, 2023 Asthma affects an estimated 262 million people worldwide and caused over 461,000 deaths in 2019. The disease is characterized by chronic airway inflammation, reversible bronchoconstriction, and airway remodeling.
Aileen Hsieh +5 more
doaj +1 more source