Results 11 to 20 of about 397,469 (244)

Airway Remodeling in Asthma and Irreversible Airflow Limitation —ECM Deposition in Airway and Possible Therapy for Remodeling—

open access: yesAllergology International, 2007
Airway remodeling in asthma is characterized by goblet cell hyperplasia, subepithelial fibrosis, and hyperplasia and hypertrophy of airway smooth muscle cells.
Kohei Yamauchi, Hiroshi Inoue
doaj   +2 more sources

Rhinovirus induces airway remodeling: what are the physiological consequences?

open access: yesRespiratory Research, 2023
Background Rhinovirus infections commonly evoke asthma exacerbations in children and adults. Recurrent asthma exacerbations are associated with injury-repair responses in the airways that collectively contribute to airway remodeling.
Cassandra Spector   +3 more
doaj   +2 more sources

Increased expression of cathepsin C in airway epithelia exacerbates airway remodeling in asthma

open access: yesJCI Insight
Airway remodeling is a critical factor determining the pathogenesis and treatment sensitivity of severe asthma (SA) or uncontrolled asthma (UA). The activation of epithelial-mesenchymal trophic units (EMTUs) regulated by airway epithelial cells (AECs ...
Lin Yuan   +16 more
doaj   +2 more sources

Research trends on airway remodeling: A bibliometrics analysis

open access: yesHeliyon
Background: Airway remodeling is an essential pathological basis of respiratory diseases such as asthma and COPD, which is significantly related to pulmonary function and clinical symptoms.
Pengcheng Liu   +7 more
doaj   +2 more sources

Pathobiology of Airway Remodeling in Asthma: The Emerging Role of Integrins [PDF]

open access: yesJournal of Asthma and Allergy, 2022
Chitra Joseph, Amanda L Tatler Centre for Respiratory Research, National Institute for Health Research Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, UKCorrespondence: Amanda L Tatler, Centre for Respiratory ...
Joseph C, Tatler AL
doaj   +2 more sources

Airway Remodeling and Airway Smooth Muscle in Asthma

open access: yesAllergology International, 2006
Airway remodeling in asthma has been recognized as structural changes of airways such as smooth muscle hypertrophy (an increase in size of airway smooth muscle cells) and hyperplasia (an increase in the number of airway smooth muscle cells), thickening ...
Mitsuru Munakata
doaj   +2 more sources

Airway Remodeling in Feline Lungs [PDF]

open access: yes, 2022
Airway remodeling encompass structural changes that occur as the result of chronic injury and lead to persistently altered airway structure and function.
Avallone G.   +5 more
core   +1 more source

Potential Role of mRNAs and LncRNAs in Chronic Intermittent Hypoxia Exposure-Aggravated Atherosclerosis

open access: yesFrontiers in Genetics, 2020
Atherosclerosis is the pathological basis of cardiovascular disease. Obstructive sleep apnea (OSA) aggravates atherosclerosis, and chronic intermittent hypoxia (CIH) as a prominent feature of OSA plays an important role during the process of ...
Jing Zhang   +31 more
doaj   +1 more source

Medicine Targeting Epithelial-Mesenchymal Transition to Treat Airway Remodeling and Pulmonary Fibrosis Progression

open access: yesCanadian Respiratory Journal, 2023
Objective. Dysregulation of epithelial-mesenchymal transition (EMT) in the airway epithelium is associated with airway remodeling and the progression of pulmonary fibrosis.
Hongjuan He   +6 more
doaj   +1 more source

Role of Th17 Cytokines in Airway Remodeling in Asthma and Therapy Perspectives

open access: yesFrontiers in Allergy, 2022
Airway remodeling is a frequent pathological feature of severe asthma leading to permanent airway obstruction in up to 50% of cases and to respiratory disability.
Victor Margelidon-Cozzolino   +4 more
doaj   +1 more source

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