Results 11 to 20 of about 365,854 (289)

Airway Remodeling in Asthma and Irreversible Airflow Limitation —ECM Deposition in Airway and Possible Therapy for Remodeling— [PDF]

open access: yesAllergology International, 2007
Airway remodeling in asthma is characterized by goblet cell hyperplasia, subepithelial fibrosis, and hyperplasia and hypertrophy of airway smooth muscle cells.
Kohei Yamauchi, Hiroshi Inoue
doaj   +2 more sources

Airway Remodeling in Feline Lungs [PDF]

open access: yesTopics in Companion Animal Medicine, 2022
Airway remodeling encompass structural changes that occur as the result of chronic injury and lead to persistently altered airway structure and function. Although this process is known in several human respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD), airway remodeling is poorly characterized in the feline ...
D'Annunzio G.   +5 more
openaire   +4 more sources

Rhinovirus induces airway remodeling: what are the physiological consequences?

open access: yesRespiratory Research, 2023
Background Rhinovirus infections commonly evoke asthma exacerbations in children and adults. Recurrent asthma exacerbations are associated with injury-repair responses in the airways that collectively contribute to airway remodeling.
Cassandra Spector   +3 more
doaj   +2 more sources

Research trends on airway remodeling: A bibliometrics analysis

open access: yesHeliyon
Background: Airway remodeling is an essential pathological basis of respiratory diseases such as asthma and COPD, which is significantly related to pulmonary function and clinical symptoms.
Pengcheng Liu   +7 more
doaj   +2 more sources

Increased expression of cathepsin C in airway epithelia exacerbates airway remodeling in asthma

open access: yesJCI Insight
Airway remodeling is a critical factor determining the pathogenesis and treatment sensitivity of severe asthma (SA) or uncontrolled asthma (UA). The activation of epithelial-mesenchymal trophic units (EMTUs) regulated by airway epithelial cells (AECs ...
Lin Yuan   +16 more
doaj   +2 more sources

Mechanisms of Airway Remodeling in Asthma [PDF]

open access: yesAllergology International, 2007
Asthma is a chronic inflammatory disease characterized by reversible airflow limitation and airway hyperresponsiveness. Persistent inflammation in airway tissues may lead to structural changes known as airway remodeling and consequently airway ...
Etsuko Tagaya, Jun Tamaoki
doaj   +2 more sources

Effect of acute and chronic pressure-threshold inspiratory muscle training on upper and lower airway function [PDF]

open access: yes, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.There is evidence to suggest that inspiratory muscle training (IMT) may influence the functional properties of the muscles of the upper (UA) and lower (LA ...
How, Stephen Christopher
core   +7 more sources

Airway remodeling in asthma [PDF]

open access: yesJournal of Clinical Investigation, 1999
Asthma is estimated to affect 15 million people in the United States. After declining in the 1970s, its prevalence, morbidity, and mortality have increased since the 1980s. It now affects 1 in 7 children in the United Kingdom, and is the most frequent reason for preventable childhood hospitalizations in the United States.
J A, Elias, Z, Zhu, G, Chupp, R J, Homer
openaire   +2 more sources

Central role of cellular senescence in TSLP-induced airway remodeling in asthma. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND:Airway remodeling is a repair process that occurs after injury resulting in increased airway hyper-responsiveness in asthma. Thymic stromal lymphopoietin (TSLP), a vital cytokine, plays a critical role in orchestrating, perpetuating and ...
Jinxiang Wu   +8 more
doaj   +1 more source

Potential Role of mRNAs and LncRNAs in Chronic Intermittent Hypoxia Exposure-Aggravated Atherosclerosis

open access: yesFrontiers in Genetics, 2020
Atherosclerosis is the pathological basis of cardiovascular disease. Obstructive sleep apnea (OSA) aggravates atherosclerosis, and chronic intermittent hypoxia (CIH) as a prominent feature of OSA plays an important role during the process of ...
Jing Zhang   +31 more
doaj   +1 more source

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