Results 31 to 40 of about 397,469 (244)

Analysis of Differentially Expressed MicroRNAs in OVA-induced Airway Remodeling Model Mice

Iranian Journal of Allergy, Asthma and Immunology, 2022
MicroRNAs (miRNAs) can participate in airway remodeling by regulating immune molecule expression. Here, we aimed to identify the differential miRNAs involved in airway remodeling. Airway remodeling was induced by ovalbumin in female BALB/C mice.
Chang Xu, Yilan Song, Chongyang Wang, Jingzhi Jiang, Zhiguang Wang, Liangchang Li, Guanghai Yan   +6 more
doaj   +1 more source

Airway Wall Remodeling in Childhood Asthma—A Personalized Perspective from Cell Type-Specific Biology

, 2021
Airway wall remodeling is a pathology occurring in chronic inflammatory lung diseases including asthma, chronic obstructive pulmonary disease, and fibrosis.
Michael Roth, Lei Fang
core   +1 more source

Aldose reductase inhibition prevents allergic airway remodeling through PI3K/AKT/GSK3β pathway in mice. [PDF]

PLoS ONE, 2013
Long-term and unresolved airway inflammation and airway remodeling, characteristic features of chronic asthma, if not treated could lead to permanent structural changes in the airways.
Umesh C S Yadav, Amarjit S Naura, Leopoldo Aguilera-Aguirre, Istvan Boldogh, Hamid A Boulares, William J Calhoun, Kota V Ramana, Satish K Srivastava   +7 more
doaj   +1 more source

Asthma remodeling: The pathogenic role of matrix metalloproteinase-9

Egyptian Journal of Chest Disease and Tuberculosis, 2014
Background: Asthma is an airway inflammatory disease with functional and structural changes, leading to bronchial hyperresponsiveness and airflow obstruction.
Amgad A. Farhat, Ahmad S. Mohamad, Mohamad M. Shareef, Ghada Atef Attia, Manal A. Eid, Rehab W. Taha   +5 more
doaj   +1 more source

Proline is increased in allergic asthma and promotes airway remodeling

JCI Insight, 2023
Proline and its synthesis enzyme pyrroline-5-carboxylate reductase 1 (PYCR1) are implicated in epithelial-mesenchymal transition (EMT), yet how proline and PYCR1 function in allergic asthmatic airway remodeling via EMT has not yet been addressed to our ...
Tingting Xu, Zhenzhen Wu, Qi Yuan, Xijie Zhang, Yanan Liu, Chaojie Wu, Meijuan Song, Jingjing Wu, Jingxian Jiang, Zhengxia Wang, Zhongqi Chen, Mingshun Zhang, Mao Huang, Ningfei Ji   +13 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

CTGF upregulation correlates with MMP-9 level in airway remodeling in a murine model of asthma

, 2016
Introduction : Connective tissue growth factor (CTGF) mediates hypertrophy, proliferation, and extracellular matrix synthesis. Matrix metalloproteinase (MMP) plays a role in airway extracellular matrix remodeling.
Bor-Luen Chiang, Sheng-Chieh Lin, Chung-Ming Chen, Hsiu-Chu Chou   +3 more
core   +1 more source

Advanced Flexible Robotic Systems for the Early Diagnosis and Treatment of Cancer and Cardiovascular Diseases

Advanced Robotics Research, EarlyView.
Flexible surgical robots are advancing minimally invasive interventions for cardiovascular diseases and cancer by enabling precise navigation through complex, submillimeter anatomical pathways. This review highlights recent innovations in actuation, bio‐integrated sensing, AI‐assisted control, and friction‐reduction technologies, discusses current ...
Hermione Truong, Chi Cong Nguyen, Hannah Thuy Truong, Kefan Zhu, Adrienne Ji, James Davies, Emanuele Nicotra, Bibhu Sharma, Jingjing Wan, Patrick Pruscino, Shing Wai Wong, Hoang‐Phuong Phan, Phuoc Thien Phan, Nigel H. Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Complete Dependence on CD4+ Cells in Late Asthmatic Response, but Limited Contribution of the Cells to Airway Remodeling in Sensitized Mice

Journal of Pharmacological Sciences, 2011
.: It is known that the late asthmatic response (LAR), a characteristic feature of asthma, is closely associated with CD4+ Th2 cell–mediated allergic inflammation. Airway remodeling is also a pathogenesis of asthma, but literature reporting roles of CD4+
Takeshi Nabe, Toyoko Morishita, Kouki Matsuya, Ayumu Ikedo, Masanori Fujii, Nobuaki Mizutani, Shin Yoshino   +6 more
doaj   +1 more source

Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling [PDF]

, 2018
Airway remodeling is responsible for the progressive decline of lung function in bronchial asthma. Matrix metalloproteinase-2 and fibroblast-to-myofibroblast transition are involved in tissue remodeling.
Tetsu Kobayashi, Atsuro Takeshita, Yu Kuwabara, Mizuho Nagao, Corina N. D'Alessandro-Gabazza, Kota Nishihama, Hajime Fujimoto, Takao Fujisawa, Taro Yasuma, Esteban C. Gabazza, Masaaki Toda   +10 more
core   +1 more source