Results 31 to 40 of about 45,718 (290)
Frontiers in Microbiology, 2021 BackgroundThe dysbiosis of respiratory microbiota plays an important role in asthma development. However, there is limited information on the changes in the respiratory microbiota and how these affect the host during the progression from acute allergic ...
Jun Zheng +5 more
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Analysis of Differentially Expressed MicroRNAs in OVA-induced Airway Remodeling Model Mice
Iranian Journal of Allergy, Asthma and Immunology, 2022 MicroRNAs (miRNAs) can participate in airway remodeling by regulating immune molecule expression. Here, we aimed to identify the differential miRNAs involved in airway remodeling. Airway remodeling was induced by ovalbumin in female BALB/C mice.
Chang Xu +6 more
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Role of Abl in airway hyperresponsiveness and airway remodeling [PDF]
Respiratory Research, 2013 Asthma is a chronic disease that is characterized by airway hyperresponsiveness and airway remodeling. The underlying mechanisms that mediate the pathological processes are not fully understood. Abl is a non-receptor protein tyrosine kinase that has a role in the regulation of smooth muscle contraction and smooth muscle cell proliferation in vitro. The
Cleary, Rachel A +3 more
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Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling [PDF]
, 2018 Airway remodeling is responsible for the progressive decline of lung function in bronchial asthma. Matrix metalloproteinase-2 and fibroblast-to-myofibroblast transition are involved in tissue remodeling.
Tetsu Kobayashi +10 more
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Pathobiology of Airway Remodeling in Asthma: The Emerging Role of Integrins
Journal of Asthma and Allergy, 2022 Chitra Joseph, Amanda L Tatler Centre for Respiratory Research, National Institute for Health Research Biomedical Research Centre, School of Medicine, University of Nottingham, Nottingham, UKCorrespondence: Amanda L Tatler, Centre for Respiratory ...
Joseph C, Tatler AL
doaj
Aldose reductase inhibition prevents allergic airway remodeling through PI3K/AKT/GSK3β pathway in mice. [PDF]
PLoS ONE, 2013 Long-term and unresolved airway inflammation and airway remodeling, characteristic features of chronic asthma, if not treated could lead to permanent structural changes in the airways.
Umesh C S Yadav +7 more
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Asthma remodeling: The pathogenic role of matrix metalloproteinase-9
Egyptian Journal of Chest Disease and Tuberculosis, 2014 Background: Asthma is an airway inflammatory disease with functional and structural changes, leading to bronchial hyperresponsiveness and airflow obstruction.
Amgad A. Farhat +5 more
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Clinical relevance of airway remodelling in airway diseases [PDF]
European Respiratory Journal, 2007 Asthma and chronic obstructive pulmonary disease (COPD) are characterised by airflow obstruction, airway remodelling (measurable structural change) and inflammation. The present review will examine the relationship between airway remodelling in these two conditions with respect to symptoms, abnormal lung function, airway hyperresponsiveness and decline
A L, James, S, Wenzel
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Proline is increased in allergic asthma and promotes airway remodeling
JCI Insight, 2023 Proline and its synthesis enzyme pyrroline-5-carboxylate reductase 1 (PYCR1) are implicated in epithelial-mesenchymal transition (EMT), yet how proline and PYCR1 function in allergic asthmatic airway remodeling via EMT has not yet been addressed to our ...
Tingting Xu +13 more
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A new series on airway remodelling [PDF]
European Respiratory Journal, 2007 In today's respiratory research, airway remodelling is probably one the best examples of an area for which the level of excitement easily matches the level of confusion on its definition and implication. This seeming contradiction may, however, not be worrying at all in science. In fact, it is likely to be a powerful driving force of creative research,
Boulet, L.-P., Sterk, P. J.
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