Results 21 to 30 of about 45,718 (290)

Research progress on miRNA in airway remodeling [PDF]

open access: yesXin yixue, 2022
Airway remodeling refers to the structural and functional changes of airway tissues caused by repeated chronic inflammatory stimulation injury and incomplete repair.
Qiu Chenhui, Chen Ye
doaj   +1 more source

Airway remodeling in asthma [PDF]

open access: yesJournal of Clinical Investigation, 1999
Asthma is estimated to affect 15 million people in the United States. After declining in the 1970s, its prevalence, morbidity, and mortality have increased since the 1980s. It now affects 1 in 7 children in the United Kingdom, and is the most frequent reason for preventable childhood hospitalizations in the United States.
J A, Elias, Z, Zhu, G, Chupp, R J, Homer
openaire   +2 more sources

Potential Role of mRNAs and LncRNAs in Chronic Intermittent Hypoxia Exposure-Aggravated Atherosclerosis

open access: yesFrontiers in Genetics, 2020
Atherosclerosis is the pathological basis of cardiovascular disease. Obstructive sleep apnea (OSA) aggravates atherosclerosis, and chronic intermittent hypoxia (CIH) as a prominent feature of OSA plays an important role during the process of ...
Jing Zhang   +31 more
doaj   +1 more source

Role of Th17 Cytokines in Airway Remodeling in Asthma and Therapy Perspectives

open access: yesFrontiers in Allergy, 2022
Airway remodeling is a frequent pathological feature of severe asthma leading to permanent airway obstruction in up to 50% of cases and to respiratory disability.
Victor Margelidon-Cozzolino   +4 more
doaj   +1 more source

Correlation between sestrin2 expression and airway remodeling in COPD

open access: yesBMC Pulmonary Medicine, 2020
Background Airway remodeling is a major pathological characteristic of chronic obstructive pulmonary disease (COPD), and has been shown to be associated with oxidative stress.
Da-Wei Zhang   +3 more
doaj   +1 more source

Salidroside Ameliorated Intermittent Hypoxia-Aggravated Endothelial Barrier Disruption and Atherosclerosis via the cAMP/PKA/RhoA Signaling Pathway

open access: yesFrontiers in Pharmacology, 2021
Background: Endothelial barrier dysfunction plays a key role in atherosclerosis progression. The primary pathology of obstructive sleep apnea-hypopnea syndrome is chronic intermittent hypoxia (IH), which induces reactive oxygen species (ROS ...
Linyi Li   +32 more
doaj   +1 more source

Airway Remodeling in Asthma and Irreversible Airflow Limitation —ECM Deposition in Airway and Possible Therapy for Remodeling—

open access: yesAllergology International, 2007
Airway remodeling in asthma is characterized by goblet cell hyperplasia, subepithelial fibrosis, and hyperplasia and hypertrophy of airway smooth muscle cells.
Kohei Yamauchi, Hiroshi Inoue
doaj   +1 more source

Airway Remodeling in Asthma: Tumor of the Airway? [PDF]

open access: yesRespiration, 2013
properties and the therapy has been shown to have an acute and sustained beneficial effect on lung function (changes in FEV 1 ) in chronic persistent asthma [6] . Antileukotrienes do not have major side effects and appear to be well tolerated by most patients [7] , but a limitation of their widespread use may be due to the large percentage of ...
Chun Y, Seow, Stephan, van Eeden
openaire   +2 more sources

Fstl1 Promotes Asthmatic Airway Remodeling by Inducing Oncostatin M. [PDF]

open access: yes, 2015
Chronic asthma is associated with airway remodeling and decline in lung function. In this article, we show that follistatin-like 1 (Fstl1), a mediator not previously associated with asthma, is highly expressed by macrophages in the lungs of humans with ...
Song, Dae   +18 more
core   +1 more source

Relationships between Airway Remodeling and Clinical Characteristics in COPD Patients

open access: yes, 2022
Background: Airway remodeling is a cardinal feature of chronic obstructive pulmonary disease (COPD) pathology. However, inconsistent findings have been reported regarding the nature of proximal airway remodeling in COPD.
Higham, Andrew; id_orcid   +8 more
core   +1 more source

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