Results 21 to 30 of about 365,854 (289)
Canadian Respiratory Journal, 2023 Objective. Dysregulation of epithelial-mesenchymal transition (EMT) in the airway epithelium is associated with airway remodeling and the progression of pulmonary fibrosis.
Hongjuan He +6 more
doaj +1 more source
Role of Th17 Cytokines in Airway Remodeling in Asthma and Therapy Perspectives
Frontiers in Allergy, 2022 Airway remodeling is a frequent pathological feature of severe asthma leading to permanent airway obstruction in up to 50% of cases and to respiratory disability.
Victor Margelidon-Cozzolino +4 more
doaj +1 more source
Children, 2022 Anti-inflammatory therapy, centered on inhaled steroids, suppresses airway inflammation in asthma, reduces asthma mortality and hospitalization rates, and achieves clinical remission in many pediatric patients.
Mitsuru Tsuge +2 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Background: Endothelial barrier dysfunction plays a key role in atherosclerosis progression. The primary pathology of obstructive sleep apnea-hypopnea syndrome is chronic intermittent hypoxia (IH), which induces reactive oxygen species (ROS ...
Linyi Li +32 more
doaj +1 more source
The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype [PDF]
, 2013 We previously demonstrated inhibition of ovalbumin (OVA)-induced allergic airway hyper-responsiveness in the mouse using ES-62, a phosphorylcholine-containing glycoprotein secreted by the filarial nematode, Acanthocheilonema viteae.
Al-Riyami, Lamyaa +8 more
core +4 more sources
Correlation between sestrin2 expression and airway remodeling in COPD
BMC Pulmonary Medicine, 2020 Background Airway remodeling is a major pathological characteristic of chronic obstructive pulmonary disease (COPD), and has been shown to be associated with oxidative stress.
Da-Wei Zhang +3 more
doaj +1 more source
Airway wall remodeling in asthma : novel mechanisms of human bronchial smooth muscle cells in the induction of angiogenesis [PDF]
, 2014 Asthma is a global major health concern and it affects estimated 300 million people. The prevalence of asthma is rising and there is no cure for asthma, only the symptoms can be controlled.
Keglowich, Laura Franziska
core +1 more source
Airway Remodeling in Asthma: Tumor of the Airway? [PDF]
Respiration, 2013 properties and the therapy has been shown to have an acute and sustained beneficial effect on lung function (changes in FEV 1 ) in chronic persistent asthma [6] . Antileukotrienes do not have major side effects and appear to be well tolerated by most patients [7] , but a limitation of their widespread use may be due to the large percentage of ...
Chun Y, Seow, Stephan, van Eeden
openaire +2 more sources
Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling [PDF]
, 2005 Background: Sub- epithelial extracellular matrix deposition is a feature of asthmatic airway remodelling associated with severity of disease, decline in lung function and airway hyperresponsiveness.
Reinhardt Alistair K +11 more
core +2 more sources
, 2021 Although HHIP locus has been consistently associated with the susceptibility to COPD including airway remodeling and emphysema in genome-wide association studies, the molecular mechanism underlying this genetic association remains incompletely understood.
Xu, S. +10 more
core +1 more source